Publications by authors named "Alida Lp Caforio"

Introduction: Heart involvement is a common problem in systemic sclerosis. Recently, a definition of systemic sclerosis primary heart involvement had been proposed. Our aim was to establish consensus guidance on the screening, diagnosis and follow-up of systemic sclerosis primary heart involvement patients.

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Article Synopsis
  • Primary heart involvement in systemic sclerosis can lead to serious cardiac issues and is a significant cause of mortality, highlighting the need for a clear definition for research purposes.
  • A systematic review and expert consensus using voting identified a definition for cardiac involvement in systemic sclerosis, achieving strong validity and reliability measures.
  • The newly proposed definition is intended to guide future clinical research and improve understanding of heart-related complications in systemic sclerosis.
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Myocarditis is an inflammatory heart disease induced by infectious and non-infectious causes frequently triggering immune-mediated pathologic mechanisms leading to myocardial damage and dysfunction. In approximately half of the patients, acute myocarditis resolves spontaneously while in the remaining cases, it may evolve into serious complications including inflammatory cardiomyopathy, arrhythmias, death, or heart transplantation. Due to the large variability in clinical presentation, unpredictable course of the disease, and lack of established causative treatment, myocarditis represents a challenging diagnosis in modern cardiology.

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