No association between Helicobacter pylori infection and gastrointestinal complaints in a large cohort of symptomatic children.

Aim: This Polish study estimated the prevalence of the Helicobacter pylori infection in symptomatic children aged 3-18 and investigated its association with gastrointestinal complaints.

Methods: We prospectively enrolled 1984 children (54% female) with a mean age of 9.5 ± 4.

Monotherapy with infliximab versus combination therapy in the maintenance of clinical remission in children with moderate to severe Crohn disease.

Objectives: The aim of the present study was to compare the efficacy and safety of 2 protocols of maintenance therapy with infliximab (IFX) and an immunomodulatory agent in pediatric patients with Crohn disease (CD): withdrawal of immunomodulators versus continuation of immunosuppressants.

Methods: The present multicenter randomized open-label trial included 99 patients with CD (ages 14.5 ± 2.