Publications by authors named "Alicja Piasecka-Belkhayat"

Article Synopsis
  • Cryopreservation is a method used to freeze and store biological cells and tissues, like stem cells and articular cartilage, to maintain their essential functions when thawed.
  • This process is particularly important in medicine for repairing damaged joints, as it allows preserved cartilage to be used for reconstruction.
  • The article discusses a study using numerical methods to analyze heat and mass transfer in cryopreserved cartilage, revealing a small relative error in thermophysical parameters and proposing modified values for better accuracy.
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This paper presents the numerical modelling of heat transfer and changes proceeding in the homogeneous sample, caused by the crystallisation phenomenon during cryopreservation by vitrification. Heat transfer was simulated in a microfluidic system in which the working fluid flowed in micro-channels. The analysed process included single-phase flow during warming, and two-phase flow during cooling.

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In the present paper, numerical modelling of heat and mass transfer proceeding in a two-dimensional axially symmetrical articular cartilage sample subjected to a cryopreservation process is presented. In the model under consideration, interval parameters were assumed. The heat transfer process is described using the Fourier interval equation, while the cryoprotectant transport (DMSO) across the cell membrane is analyzed using a two-parameter model taking into account the simulation of the water volume in the chondrocytes and the change in DMSO concentration over time.

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Numerical analysis of heat transfer processes proceeding in a nonhomogeneous biological tissue domain is presented. In particular, the skin tissue domain subjected to an external heat source is considered. The problem is treated as an axially-symmetrical one (it results from the mathematical form of the function describing the external heat source).

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