Publications by authors named "Alicia Snowden"
Article Synopsis
- The study examines the rising rates of early onset colorectal cancer (EOCRC) among African American patients, highlighting significant differences between EOCRC (<45 years) and late-onset colorectal cancer (LOCRC) (>45 years) in terms of demographics and clinical presentation.
- It found that EOCRC cases increased from just over 6% to over 13% of total CRC cases since 2010, with a higher family history of CRC and different symptom profiles, such as more abdominal pain and changes in bowel habits.
- The study also noted that EOCRC patients had a higher rate of metastasis at diagnosis and took longer to undergo surgery compared to LOCRC patients.
Patients with multiple myeloma (MM) are typically of an advanced age and may have significant co-existing medical conditions. They have often had multiple lines of therapy and as such experience disease-related effects alongside associated treatment toxicities. Daratumumab is a monoclonal antibody approved for the treatment of MM in the relapsed/refractory setting.
View Article and Find Full Text PDFPatients with chronic lymphocytic leukaemia (CLL) are typically diagnosed at an advanced age and may have multiple co-existing conditions, augmenting the challenges of treating their CLL. Aggressive cytotoxic therapies are often poorly tolerated in this patient population. Obinutuzumab is a glycoengineered type II anti-CD20 monoclonal antibody indicated in combination with chlorambucil for previously untreated CLL.
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