Publications by authors named "Alicia Podwojniak"
Article Synopsis
- Continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusions (CSII) are essential treatments for type 1 diabetes (T1D), but they may cause dermatologic complications like contact dermatitis and lipodystrophies, which negatively affect glycemic control and patient adherence.
- A systematic review analyzed 30 studies focusing on dermatologic issues related to CGM and CSII in pediatric patients, finding that contact dermatitis was the most common complication reported.
- The findings highlight the need for better manufacturer transparency and further research to address how these skin complications may impact long-term T1D management in young patients.
Objective: To investigate the benefits of topical 8% capsaicin patches for the decrease of postsurgical neuropathic pain level and area.
Methods: A systematic review with pooled analysis was conducted utilizing the PRISMA 2020 guidelines. Five commonly used databases were employed utilizing a search string made from MeSH terms and boolean operators.
Keloids are thickened raised scars that develop due to injury and grow beyond the boundaries of their original wound, mostly affecting individuals with skin of color. This review explores the use of energy-based devices to treat keloids, both using laser monotherapy and in combination with other drugs. Laser therapy alone has shown efficacy in treating keloids.
View Article and Find Full Text PDFAcne and the cutaneous microbiome: A systematic review of mechanisms and implications for treatments.
J Eur Acad Dermatol Venereol
September 2024
Article Synopsis
- Acne vulgaris is a common skin problem that causes pimples and is linked to the bacteria on our skin.
- Current treatments for acne work but have some problems, so researchers are looking at using skin bacteria to create new options.
- A review of many studies showed that some treatments can change the types of bacteria on the skin, and new ideas like using probiotics might help clear up acne too.
Article Synopsis
- - Psoriasis is an inflammatory skin disease treated with topical medications like steroids and vitamin D analogs; new treatments such as tapinarof and roflumilast have shown promise with their unique anti-inflammatory effects.
- - A review of recent studies identified strong efficacy and manageable side effects for both tapinarof and roflumilast in mild-to-moderate plaque psoriasis, with tapinarof having more frequent, mild side effects, while roflumilast had less frequent but more severe adverse events.
- - Both treatments allow for once-daily dosing which could improve patient adherence, but cost is a concern; further research is needed to compare their effectiveness, safety, and overall cost-effectiveness.
Article Synopsis
- Acne vulgaris is a complex skin condition with both inflammatory and noninflammatory lesions, and using combination topical therapies can effectively target multiple causes in a single treatment.
- Clindamycin phosphate/benzoyl peroxide/adapalene is the first FDA-approved triple therapy that shows significant effectiveness against acne while having a low side effect profile.
- A literature review from 2018 to 2023 examined various combination treatments and found that these multi-drug formulations improve patient adherence and offer a promising solution for managing acne vulgaris.
Article Synopsis
- - The text discusses the evolution of personalized medicine in dermatology, emphasizing how biomarkers are used not just for diagnosis but also for staging diseases and monitoring treatment effectiveness.
- - It reviews the role of specific biomarkers in various skin conditions such as Hidradenitis Suppurativa, Psoriasis, and Atopic Dermatitis, highlighting their influence on targeted therapies like adalimumab and dupilumab.
- - The future of dermatological care looks promising with advancements in AI, nanotechnology, and multi-omics, aiming to enhance the precision of individualized treatments.
Article Synopsis
- AI technology is being widely used in dermatology for assessing and diagnosing skin conditions, utilizing algorithms and language models to mimic human problem-solving.
- A literature review highlighted challenges faced by AI programs, particularly their difficulty in accurately identifying skin lesions in skin of color (SOC) due to underrepresentation in data sets.
- Only 30% of existing programs reported effectiveness in SOC, indicating a need for improved image quality and more inclusive datasets for better AI performance in dermatology.
Article Synopsis
- - Trichotillomania (TTM) is a psychiatric disorder that causes hair pulling, affecting about 1-3% of the population and often linked to emotional distress and other mental health conditions.
- - A systematic review of the literature found that treatments like N-acetyl cysteine (NAC), aripiprazole, and monoamine oxidase inhibitors show promise, with NAC being particularly effective when used alongside other therapies.
- - Future treatment strategies for TTM should integrate pharmacological approaches with behavioral therapies, while also considering patients' other mental health issues for better outcomes.
Background Although White individuals have higher incidence of melanoma, clinical outcomes are worse among patients with skin of color. This disparity arises from delayed diagnoses and treatment that are largely due to clinical and sociodemographic factors. Investigating this discrepancy is crucial to decrease melanoma-related mortality rates in minority communities.
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