Publications by authors named "Alicia Peschel"

Article Synopsis
  • Voltage-gated sodium channels are crucial for cell activities and are targeted by various drugs for conditions like epilepsy.
  • Researchers designed a new type of ligand by combining a toxin that blocks sodium channels with another peptide that enhances their function, using innovative chemical methods to create a stronger connection between them.
  • The resulting ligand showed improved effectiveness, being 4-24 times more potent and binding more tightly than existing solutions, demonstrating the potential of this new design approach in drug development.
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