Publications by authors named "Alicia Langer"
Biology (Basel)
September 2024
Article Synopsis
- A study found that 7% of spontaneously hypertensive rats (SHRs) develop severe right ventricular hypertrophy (RVH) alongside left ventricular hypertrophy, indicating that RVH can occur independently.
- Researchers examined the molecular characteristics of the lungs and right ventricles of SHR rats with RVH and compared them to both SHRs with only left ventricular hypertrophy and normotensive rats.
- Results indicated low expression of the endothelin-B receptor in the lungs of SHR rats with RVH, suggesting it might lead to increased vascular resistance and subsequently trigger RVH, marking the first genetic variant described in this specific SHR strain.
