New insights in the pathogenic mechanism of multiple sclerosis: Is Epstein-Barr virus associated with optic nerve involvement?

Introduction: There are no reports in the literature studying the possible relationship between Epstein-Barr virus (EBV) and optic nerve involvement in multiple sclerosis (MS). The aim of our study was to analyze the association between EBV antibodies titres and optical coherence tomography (OCT) and OCT angiography (OCTA) quantitative parameters.

Methods: We conducted a retrospective study.

Optical coherence tomography angiography analysis in patients with intracranial hypertension.

Introduction: Evidence on peripapillary microvasculature in intracranial hypertension (IH) after the regression of papilledema is still scarce. The aim of this preliminary study was to determine the association between structural changes in the optic nerve and the retina and peripapillary microvasculature in patients with IIH.

Methods: We conducted a retrospective study.

Case Report: Optic Nerve Atrophy Secondary to Sjögren Syndrome.

Significance: Optic neuropathy associated with Sjögren syndrome is rare and usually has an acute onset.

Purpose: This study aimed to report a case of asymmetric optic nerve atrophy attributed to Sjögren syndrome.

Case Report: A 37-year-old woman was referred to neuro-ophthalmology service because of right optic nerve atrophy of unknown etiology.

Rituximab in the treatment of Susac's syndrome: Report of a case.

Significance: Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's syndrome has persisted as an elusive entity and there are numerous treatment regimens proposed with varying effectiveness mainly based on case series.

Functional and structural changes in the visual pathway in multiple sclerosis.

Introduction: Multiple sclerosis (MS) is a heterogeneous disease with an unpredictable course. Visual pathway is a target of the disease and may reflect mechanisms that lead to disability. Structural and functional changes in the visual pathway may be studied by noninvasive techniques such as optical coherence tomography (OCT), visual evoked potentials (VEP), or B-mode transorbital sonography (TOS).

An objective scatter index cutoff point as a powerful objective criterion for preoperative nuclear cataract decision-making based on ROC analysis.

Purpose: To assess the correlation between clinical cataract surgery indication and the objective scatter index (OSI) by defining the optimal OSI cutoff point in the surgery scheduling.

Setting: Ophthalmology service, Consorcio Hospital General Universitario, Valencia, Spain.

Design: Prospective triple-masked randomized single-center study.