Publications by authors named "Alicia G Facca"

Objective: To describe temporal profile of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in patients with definite, relapsing multiple sclerosis (MS).

Background: Peripheral demyelinating neuropathy has been rarely reported in association with central nervous system demyelinating disorder indistinguishable from MS.

Methods: In addition to usual diagnostic studies for CIDP and MS in all 5 patients, we studied proximal segments of nerves using deep tendon reflex latency measurements of biceps reflex, patellar reflex, and ankle reflex.

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Article Synopsis
  • Small-fiber neuropathy (SFN) is identified through clinical signs and specific small-fiber tests rather than standard nerve conduction studies, which are normal in these cases.
  • This study assessed deep tendon reflex (DTR) latency as a diagnostic tool for SFN by measuring reflexes in 18 SFN patients and 38 control subjects, finding that latencies were significantly longer in SFN patients across all tested reflexes.
  • Results show that DTR latency measurements are reliable and can indicate subclinical large fiber involvement, making it a useful method for diagnosing mild cases of SFN.
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