Publications by authors named "Alicia Fernandez-Sein"

Hemophagocytic Syndrome (HS) is a clinico-pathologic entity characterized by activation of T lymphocytes and macrophages. It may be diagnosed in association with malignant, genetic, or autoimmune diseases, but is most linked with Epstein-Barr virus. There are few reports of association between HS and Dengue in pediatrics.

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Malnutrition is a well-known cause of infant morbidity and mortality. In developed societies malnutrition still exists, especially in patients fed insufficient diets during chronic and critical illnesses. Malnutrition impacts all organs.

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Background: Sickle cell disease (SCD) patients suffer complications requiring simple and/or exchange transfusion. In 1999 we developed an automated exchange technique using infusion pumps and vascular catheters (IV Pump Method).

Objective: To prove that IV Pump Method is cost-efficient, and as safe and effective as automated cell separators.

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Infection-associated hemophagocytic syndrome is a rare, potentially fatal complication of systemic infection. It occurs most often in immunocompromised patients associated with a viral infection but the spectrum of conditions have been broadened to include virtually every type of infectious pathogen, malignancy and immunosuppressive therapy. We present three pediatric patients with a similar clinical history of pancytopenia, hepatosplenomegaly, and acute liver failure, and discuss the autopsy findings.

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Objective: Asses if Abdominal Compartment Syndrome (ACS) increases the morbidity and mortality of the Pediatric Intensive Care Unit patients and if early recognition and intervention with decompressive therapy will alter outcome and decrease mortality.

Setting: Pediatric Intensive Care Unit of the University Pediatric Hospital-UPR.

Patients: All patients admitted to the PICU from July 1, 1999 to June 30, 2002 were enrolled in the study.

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We present the case of an eighteen day old baby boy hospitalized with an abdominal mass, renal insufficiency and jaundice. Multiple radiographic, radionuclear and surgical interventions were required to diagnose renohepaticopancreatic dysplasia, also known as Ivemark II syndrome. In spite of aggressive intensive care support, the patient developed multisystemic organ failure and died.

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A retrospective study of the experience at the University Pediatric Hospital during a six-year period when 2529 patients were admitted to the Pediatric Intensive Care Unit (PICU) and 80 were diagnosed with brain death. Etiologic causes, age and sex distribution and use of confirmatory studies were evaluated. The specific criterias for brain death determination in children are discussed and it was found that 3.

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