Publications by authors named "Alicia D Zimmerman"
Objective: To evaluate immunity induced by a multivalent vaccine containing a US Leptospira borgpetersenii serovar Hardjo type hardjo bovis (LHB) isolate in heifers challenged 12 months after vaccination.
Design: Prospective vaccine challenge study.
Animals: 36 one-month old Holstein heifers.
Article Synopsis
- The study involved 59 crossbred beef heifers vaccinated with either a modified live virus (MLV) or inactivated virus vaccine during synchronization and breeding.
- Heifers receiving the MLV vaccine exhibited lower pregnancy rates (48%) and a higher incidence of abnormal estrous cycles (38%) compared to those given the inactivated vaccine (one-dose: 86%, two-dose: 90%).
- Overall, heifers vaccinated with the inactivated virus were more successful in achieving pregnancy, suggesting that MLV vaccination negatively impacts reproductive success in naïve heifers.
Objective: To evaluate the efficacy of vaccination with the Leptospira interrogans serovar hardjo type hardjoprajitno component of a pentavalent Leptospira bacterin against a virulent experimental challenge with Leptospira borgpetersenii serovar hardjo type hardjo-bovis strain 203 in cattle.
Animals: Fifty-five 6-month-old Holstein heifers.
Procedures: Heifers that were negative for persistent infection with bovine viral diarrhea virus determined via immunohistochemical testing and negative for Leptospira interrogans serovar pomona, Leptospira interrogans serovar hardjo, Leptospira interrogans serovar grippotyphosa, Leptospira interrogans serovar bratislava, Leptospira interrogans serovar canicola, and Leptospira interrogans serovar icterohaemorrhagiae determined via microscopic agglutination assay were enrolled in the study.
Objective: To evaluate the efficacy of an inactivated bovine herpesvirus-1 (BHV-1) vaccine to protect against BHV-1 challenge-induced abortion and stillbirth.
Design: Prospective study.
Animals: 35 beef heifers.
Objective: To evaluate the efficacy of an adjuvanted modified-live bovine viral diarrhea virus (BVDV) vaccine against challenge with a virulent type 2 BVDV strain in calves with or without maternal antibodies against the virus.
Design: Challenge study.
Animals: 23 crossbred dairy calves.