Publications by authors named "Alicia C Wells"
Article Synopsis
- Nonfunctional pituitary neuroendocrine tumors (PitNETs), especially silent corticotroph adenomas (SCAs), exhibit distinct growth patterns, with SCAs showing more aggressive invasion into areas like the sphenoid and cavernous sinuses.
- A study analyzed 91 patients who underwent surgery for nonfunctional PitNETs, comparing SCAs with other nonfunctional pituitary adenomas (NFPAs), finding significant differences in growth patterns.
- SCAs are more likely to invade bony structures, while NFPAs tend to grow into the suprasellar space, leading to varying clinical challenges in treatment strategies.
Adolescence is characterized by a critical period of maturation and growth, during which regions of the brain are vulnerable to long-lasting cognitive disturbances. Adolescent exposure to nicotine can lead to deleterious neurological and psychological outcomes. Moreover, the nicotinic acetylcholine receptor (nAChR) has been shown to play a functionally distinct role in the development of the adolescent brain.
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- - Maternal tobacco and nicotine use during pregnancy significantly increases the risk of negative birth outcomes such as miscarriage, low birth weight, and conditions like ADHD and anxiety in infants.
- - Approximately 7.2% of women in the U.S. smoke during pregnancy, with a smaller percentage using e-cigarettes, highlighting the widespread exposure to nicotine products.
- - The review focuses on how prenatal nicotine exposure affects brain development and behavior, linking it to potential long-term neurodevelopmental disorders and specific brain region alterations.