Regional Near-surface Dose Predicts Moist Desquamation and Implant Failure in Patients Receiving Radiation Therapy for Breast Cancer.

Purpose/objective: We correlated regional near-surface dose with toxic effects and implant complications in patients receiving breast or chest wall irradiation. We also compared toxic effects and implant complications between patients receiving photon or proton irradiation with prospective near-surface dose optimization.

Materials/methods: Patients at a single institution who received conventionally fractionated breast or chest wall and regional nodal irradiation from 2017-2022 were included.