Phenolphthalein Conjugated Schiff Base as a Dual Emissive Fluorogenic Probe for the Recognition Aluminum (III) and Zinc (II) Ions.

In this study, a new phenolphthalein derivative, FFIZNA, has been planned and successfully prepared in an uncomplicated way. The probe FFIZNA could selectively monitor Al and Zn among other relevant cations with diverse colors through a turn-on emission response in EtOH:HEPES (9/1;v/v) media owing to the chelation enhanced fluorescence (CHEF), prevention of ESIPT, -C=N- isomerization and PET of the probe FFIZNA. The interactions of Al and Zn with the probe FFIZNA were confirmed by emission spectroscopy, Job's plot and H-NMR titration substantiated 1:2 reaction stoichiometry between FFIZNA and Al and Zn.

The pharmacists' ability to use pressurized metered-dose inhalers with a spacer device and factors affecting it.

The aim of this study is to evaluate the pharmacists' ability to use pMDIs with a spacer device and the factors that affect this ability. Face to face interviews were conducted with the pharmacists. A nine item questionnaire was completed and the checklist for how to use pMDIs with a spacer device was filled out.

Analysis of geographical variations in the epidemiology and management of non-valvular atrial fibrillation: results from the RAMSES registry.

Objective: This study aimed to determine the differences in terms of demographic characteristics and preferred stroke prevention strategies for patients with non-valvular atrial fibrillation living in seven geographical regions of Turkey.

Methods: In total, 6273 patients were enrolled to this prospective, observational RAMSES study. The patients were divided into seven groups based on the geographical region of residence.

The Time in Therapeutic Range and Bleeding Complications of Warfarin in Different Geographic Regions of Turkey: A Subgroup Analysis of WARFARIN-TR Study.

Background: The time in therapeutic range values may vary between different geographical regions of Turkey in patients vitamin K antagonist therapy.

Aims: To evaluate the time in therapeutic range percentages, efficacy, safety and awareness of warfarin according to the different geographical regions in patients who participated in the WARFARIN-TR study (The Awareness, Efficacy, Safety and Time in Therapeutic Range of Warfarin in the Turkish population) in Turkey.

Study Design: Cross-sectional study.

Real-World Clinical Characteristics and Treatment Patterns of Individuals Aged 80 and Older with Nonvalvular Atrial Fibrillation: Results from the ReAl-life Multicenter Survey Evaluating Stroke Study.

Objectives: To compare the clinical characteristics of and use of oral anticoagulant (OAC) therapy in individuals aged 80 and older with atrial fibrillation (AF) with those of individuals younger than 80 with AF in clinical practice.

Design: Observational study.

Setting: The ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey trial (NCT02344901), a national observational registry.

Guideline-adherent therapy for stroke prevention in atrial fibrillation in different health care settings: Results from RAMSES study.

Objective: No studies have been conducted in Turkey to compare the quality of stroke prevention therapies provided in different healthcare settings in patients with atrial fibrillation (AF). Therefore, we aimed to evaluate possible differences between secondary (SH) and tertiary hospital (TH) settings in the effectiveness of implementing AF treatment strategies.

Methods: Baseline characteristics of 6273 patients with non-valvular AF enrolled in the RAMSES (ReAl-life Multicentre Survey Evaluating Stroke Prevention Strategies in Turkey) study were compared.

Recurrent giant sinus of Valsalva aneurysm and ankylosing spondylitis.

A 48-year-old woman underwent aneurysmectomy and primary suture repair with a pericardial patch for sinus of Valsalva aneurysm secondary to ankylosing spondylitis. The sinus of Valsalva aneurysm recurred one year after surgery, and reached a diameter of 53 mm. Special attention must be paid to the potential relapse of aortic aneurysms that develop secondary to autoimmune disorders, when using primary suture or patch repair.

Assessment of pollution in Ataturk Dam Lake (Adiyaman, Turkey) using several biochemical parameters in common carp, Cyprinus carpio L.

Ataturk Dam Lake, the largest impounded lake in Turkey, has been contaminated by domestic, industrial and agricultural effluents coming from Adiyaman city. In this study, we investigated the possible effects of pollutants on several biochemical parameters in the cyprinid fish, Cyprinus carpio, by comparing the parameters in fish collected from a polluted area (Sitilce) to a relatively clean area (Samsat) in August 2011. The activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and lactate dehydrogenase and levels of cortisol, glucose, and K increased while total protein, cholesterol, Ca, Na and Cl levels decreased in fish from the Sitilce site when compared to the Samsat site.

Fragmented QRS is predictive of myocardial dysfunction, pulmonary hypertension and severity in mitral stenosis.

Reliable non-invasive new indices reflecting severity of rheumatic valve disease would be highly beneficial. Recently, presence of fragmented QRS (fQRS) in ECG was accepted as a marker of myocardial fibrosis. fQRS is defined as the presence of RSR' patterns such as additional R wave (R'), notching in the R wave or the S wave in 2 contiguous leads.