This paper intends to outline a data integration response to the demands placed on the pastoral care department through the COVID-19 pandemic. Uniquely, these demands accelerated the need to implement documentation of care directed towards staff to complement the data derived from patient visitation. The motivation for this initiative is in part, to provide a complete picture of the care provided by hospital chaplains using an evidence-based approach through the implementation of data science.
View Article and Find Full Text PDFEstrogen (E2) has been demonstrated to possess protective effects from hypoglycemic toxicity, particularly in the pancreas. In the central nervous system, several brain regions, such as the hypothalamus, are highly vulnerable to hypoglycemic injuries that may lead to seizures, coma, and mortality. The present study performed a novel in vitro assay of hypoglycemic injury to hypothalamic cells, and is the first study, to the best of our knowledge, to demonstrate that E2 protects hypothalamic cells from hypoglycemic toxicity.
View Article and Find Full Text PDFAsymmetric hydroboration of 1,3-cyclohexadiene with 4R produces the allylborane 5RR as essentially a single diastereomer (i.e., no observable 5RS), and its addition to representative aldehydes provides 9RS (52-75%) with excellent selectivity (94-99% ee).
View Article and Find Full Text PDFPhytoestrogens, phthalates, and phenols are estrogen-disrupting chemicals that have a pronounced effect at puberty. They are exogenous chemicals that are either plant-derived or man-made, and can alter the functions of the endocrine system and cause various health defects by interfering with the synthesis, metabolism, binding, or cellular responses of natural estrogens. Phytoestrogens, phthalates, and phenols are some of the potent estrogens detectable in urine.
View Article and Find Full Text PDFThe synthesis of mixed borabicyclodecane (BBD)-derived 1,3-diborylpropenes (trans-1) is described. These new bimetallic reagents are effective for the selective asymmetric allylboration first of ketones (or ketimines) and second of aldehydes (or aldimines). Formed as a thermodynamic mixture of trans regioisomers from cis-1 through a series of 1,3-borotropic shifts, only trans-1 undergoes the monoallylation of ketones.
View Article and Find Full Text PDFBackground: The Berlin Questionnaire [an outcome of a primary care physicians' conference held in Berlin, Germany, in 1996 that was created to identify patients at high risk for sleep disordered breathing (SDB)] was administered to a representative sample of middle-age population in Puerto Rico in order to document the prevalence of SDB and its associated risk factors.
Materials And Methods: The island was divided in six regions to maintain heterogeneity and to have a representative sample of the population per region. Puerto Rican subjects between 30-60 years old were recruited in shopping malls, and questionnaires were filled.
Simple and efficient Grignard procedures are reported for the syntheses of B-allenyl-10-(phenyl)-9-borabicyclo[3.3.2]decane (1) and its B-(gamma-trimethylsilylpropargyl) counterpart (2) in both enantiomeric forms.
View Article and Find Full Text PDFA 71-year-old male with coronary artery disease, hypertension, diabetes mellitus, tobacco and opioid dependence came to the emergency room complaining of one episode of retrosternal chest pain oppressive in nature of one day of evolution. He had acute respiratory distress and required mechanical ventilation. The initial impression was myocardial ischemia, but electrocardiography and cardiac enzymes ruled it out.
View Article and Find Full Text PDFContext: Gulf War veterans' illnesses (GWVI), multisymptom illnesses characterized by persistent pain, fatigue, and cognitive symptoms, have been reported by many Gulf War veterans. There are currently no effective therapies available to treat GWVI.
Objective: To compare the effectiveness of cognitive behavioral therapy (CBT), exercise, and the combination of both for improving physical functioning and reducing the symptoms of GWVI.
A survey about tuberculosis infection status, surveillance and protection practices among pulmonologists and infectologists was performed.A fourteen-item questionnaire was mailed. The survey was addressed to 108 pulmonologists and 61 infectologists.
View Article and Find Full Text PDFObjectives: To assess the medical knowledge about asthma among residents from the Accreditation Council on Graduate Education (ACGME) accredited Internal Medicine programs.
Background: Asthma prevalence and morbidity has increased significantly in the last 20 years. Recent morbidity data suggests that approximately 14 to 15 million Americans suffer from asthma and 5,000 of them die annually due to this illness.
Approximately one in 250 people with autoimmunity involving their red cells have IgG autoantibodies with specificity in the Kell blood groups. Red cells of these individuals have an acquired temporary weakening of their Kell antigens. Some of the patients also have allo-anti-K in their serum.
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