Effect of micro-osteoperforations on the gene expression profile of the periodontal ligament of orthodontically moved human teeth.

Objectives: This study aimed to evaluate the effect of micro-osteoperforations (MOPs) on the gene expression profile of the periodontal ligament (PDL) of orthodontically moved teeth.

Materials And Methods: Fifteen participants were randomly assigned into two groups: tooth movement only (Tr1, n = 7) and tooth movement supplemented with MOPs (Tr2, n = 8). In each subject, orthodontic tooth movement (OTM) was performed on premolar in one side, while no force was applied on contralateral premolar (Unt, n = 15).

Global gene expression profile of periodontal ligament cells submitted to mechanical loading: A systematic review.

Objective: To evaluate the evidence reporting gene expression array data of human in vitro cultured periodontal ligament cells (PDLCs) submitted to static mechanical loading compared to a control group.

Design: Systematic searches were performed in MEDLINE/PubMed, Scopus, Web of Science, Virtual Health Library, The Cochrane Library and the System for Information on Grey Literature in Europe up to June 2019. A narrative synthesis was performed to summarize differentially expressed genes (DEGs).

Influence of orthodontic loading on biomarkers levels around miniscrews.

Objective: The aim of this study was to evaluate the levels of Interleukin-1α (IL-1α), Interleukin-1β (IL-1β), Interleukin-1 receptor antagonist (IL-1Ra), Interleukin-10 (IL-10), Interleukin-13 (IL-13), Vascular endothelial growth factor (VEGF), Granulocyte-colony stimulating factor (G-CSF), and Growth related oncogene (GRO) in the peri-miniscrew implant crevicular fluid (MICF) under orthodontic loading.

Design: The study sample comprised 14 miniscrews immediately loaded and 17 unloaded ones. A load of 200gF was immediately applied to the miniscrews in the loaded group after the placement surgery.

Reproducibility of digital indirect bonding technique using three-dimensional (3D) models and 3D-printed transfer trays.

Objective: To evaluate the reproducibility of digital tray transfer fit on digital indirect bonding by analyzing the differences in bracket positions.

Materials And Methods: Digital indirect bonding was performed by positioning brackets on digital models superimposed by tomography using Ortho Analyzer (3Shape) software. Thirty-three orthodontists performed indirect bonding on prototyped models of the same malocclusion using prototyped transfer trays for two types of brackets (MiniSprint Roth and BioQuick self-ligating).