Understanding maternal Ethnomedical Folklore in Central Uganda: a cross-sectional study of herbal remedies for managing Postpartum hemorrhage, inducing uterine contractions and abortion in Najjembe sub-county, Buikwe district.

Unlabelled: Pregnant women in rural Uganda largely rely on medicinal plants for inducing labor, treating postpartum hemorrhage (PPH), and inducing abortion. 90% of the women in both rural and urban Uganda use plants to manage pregnancy symptoms like constipation, heartburn, morning sickness, body aches, nausea, and vomiting. After delivery women continue using plants to manage postpartum complications and for infant care especially herbal baths.

Acute and subacute toxicity profile of ethanolic stem bark extract of Welw. ex Oliv. in Wistar albino rats.

(Fabaceae) crude extracts are key ingredients of several licensed and unlicensed herbal products in East Africa. However, there is limited and often contradicting information regarding its toxicity. We therefore evaluated the acute and subacute toxicity of the ethanolic stem bark extract of in mature healthy Wistar albino rats following Lorke's method and OECD guidelines 407.

Ex vivo and in vitro antiplasmodial activity and toxicity of Caesalpinia decapetala (Roth) Alston (Fabaceae).

Ethnopharmacological Relevance: Malaria is among the most prevalent and devastating parasitic diseases globally with most cases reported in Sub-Saharan Africa. One of the major reasons for the high malaria prevalence is the ever-increasing emergence of resistant strains of malaria-causing parasites to the currently used antimalarial drugs. This, therefore, calls for the search for antimalarial compounds with alternative modes of action.

Medicinal plants used for treatment of malaria by indigenous communities of Tororo District, Eastern Uganda.

Background: Malaria remains the leading cause of death in sub-Saharan Africa. Although recent developments such as malaria vaccine trials inspire optimism, the search for novel antimalarial drugs is urgently needed to control the mounting resistance of Plasmodium species to the available therapies. The present study was conducted to document ethnobotanical knowledge on the plants used to treat symptoms of malaria in Tororo district, a malaria-endemic region of Eastern Uganda.

Medically important bacteria isolated from commercial herbal medicines in Kampala city indicate the need to enhance safety frameworks.

The high global bacterial infection burden has created need to investigate the neglected potential drivers of pathogenic bacteria, to inform disease prevention. Kampala is facing a proliferation of herbalists, selling herbal medicine (HM), of largely unregulated microbiological quality. We evaluated the bacterial contamination burden in HM sold in Kampala, to support evidence-based redress.

Antibiotic-resistance in medically important bacteria isolated from commercial herbal medicines in Africa from 2000 to 2021: a systematic review and meta-analysis.

Background: Antimicrobial resistance is swiftly increasing all over the world. In Africa, it manifests more in pathogenic bacteria in form of antibiotic resistance (ABR). On this continent, bacterial contamination of commonly used herbal medicine (HM) is on the increase, but information about antimicrobial resistance in these contaminants is limited due to fragmented studies.

Phytochemical, Cytotoxicity, Antioxidant and Anti-Inflammatory Effects of Magic Mushroom.

Psilocybin-containing mushrooms, commonly known as magic mushrooms, have been used since ancient and recent times for depression and to improve quality of life. However, their anti-inflammatory properties are not known. The study aims at investing cytotoxicity; antioxidant; and, for the first time, anti-inflammatory effects of , a psilocybin-containing mushroom that grows in South Africa, on lipopolysaccharide-induced RAW 264.

Antioxidant and Anti-Inflammatory Activities of (Lam.) Benth.

is used to manage inflammation among indigenous communities. We hypothesized that extracts contain phytoconstituents with good antioxidant and anti-inflammatory activities. The methanolic extract of fruits and leaves (SPK04), aqueous fruit extract (KFM02), and acetone fruit extract (KFM05) were subjected to antioxidant and anti-inflammatory assays.

Ethnobotany, Phytochemistry and Pharmacological Activity of (Lam.) Benth. (Bignoniaceae).

has been used in the management of human ailments since time immemorial. Ethnobotanists have documented the traditional uses of , which include treatment of skin disorders, cancer and gynecological complaints, among others. This has interested scientists, who have examined plant parts for their bioactivity.