Publications by authors named "Alice Milligan"

Article Synopsis
  • Laboratory confirmation through PCR testing is essential for diagnosing and managing herpes simplex virus (HSV) keratitis, though previous sensitivity rates were low.
  • An educational intervention targeting swab technique for sample collection was implemented, leading to a retrospective review of keratitis cases before and after the program.
  • The findings showed a significant increase in lab-confirmed HSV diagnoses post-intervention, indicating that improved swabbing techniques enhanced the sensitivity of PCR testing for HSV-1 in keratitis.
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Background: Gonorrhoea is on the rise: between 2021 and 2022, a 50% and a 33% increase in diagnoses was seen, respectively, in England and the Netherlands. A concurrent rise in gonococcal keratoconjunctivitis (GKC) is a serious concern due to the potentially devastating visual complications.

Methods: This is a retrospective case series of adult GKC from two Western European tertiary ophthalmology centres between 2017 and July 2023.

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Background: Orbital compartment syndrome is a potentially blinding eye condition. Timely diagnosis and treatment are paramount to optimize visual outcomes. Lateral canthotomy and cantholysis is the definitive management and a required competency for emergency physicians and ophthalmologists.

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The 2022 outbreak of monkeypox is of worldwide significance. There has been a rapid escalation in case numbers despite efforts to contain it and the WHO has declared it a Public Health Emergency of International Concern. To date, over 51 257 laboratory-confirmed cases have been reported, the majority in non-endemic countries, with 3279 in the UK.

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Purpose: To report the case of an immunocompetent adult presenting with endogenous endophthalmitis.

Observations: A woman in her thirties presented with symptoms and signs of a unilateral anterior uveitis. After initial improvement with topical corticosteroids, she continued to develop a panuveitis with an associated drop in vision to counting fingers.

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