Publications by authors named "Alice Matthews"

Article Synopsis
  • Real-time monitoring of infectious diseases in schools faces challenges like delayed reporting and limited resources, making wastewater surveillance a viable alternative for tracking pathogens.* -
  • This study examined whether wastewater from six elementary schools could detect influenza A and B viruses, successfully identifying influenza A RNA in three schools that correlates with increased cases in the community.* -
  • Genome sequencing revealed a specific vaccine-resistant strain of influenza A (H3N2) present, highlighting the potential of wastewater surveillance to improve local disease monitoring in educational settings.*
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Various factors may alter the risk for cardiovascular disease in adults with Down syndrome (Ds), yet few studies have examined differences in cardiac physiology in this population. Previous research suggested lower systolic and diastolic function, but inconsistent methodologies and younger samples warrant research in adults with Ds. Our aim is to compare the cardiac structure and function of adults with Ds to age- and sex-matched adults without Ds.

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We investigated the in vivo relevance of the impact of sarA and saeRS on protease production using derivatives of the USA300 strain LAC. The results confirmed that mutation of saeRS or sarA reduces virulence in a bacteremia model to a comparable degree. However, while eliminating protease production restored virulence in the sarA mutant, it had little impact in the saeRS mutant.

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