The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 Replicative Cycle.

Herpes simplex virus type-1 (HSV-1) infection causes several disorders, and acyclovir is used as a reference compound. However, resistant strains are commonly observed. Herein, we investigate the effects of -heterocyclic compounds (pyrazolopyridine derivatives), named , , and , on HSV-1 in vitro replication.