A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study.

Background: A pro-inflammatory diet has been posited to induce chronic inflammation within the central nervous system (CNS), and multiple sclerosis (MS) is an inflammatory disease of the CNS.

Objective: We examined whether Dietary Inflammatory Index (DII) scores are associated with measures of MS progression and inflammatory activity.

Methods: A cohort with a first clinical diagnosis of CNS demyelination was followed annually (10 years,  = 223).