Publications by authors named "Alice Le Nir"
J Biomed Mater Res A
October 2021
Article Synopsis
- Microbeads made of pullulan and dextran, enhanced with hydroxyapatite, were tested for bone tissue engineering by injecting them with either saline or autologous blood in two animal models.
- In a rat model, imaging showed significant bone mineralization around and within the microbeads after 30 and 60 days, with no difference between the saline and blood injections.
- In a sheep model, after 3 months, both groups showed bone formation in and around the microbeads, leading to the conclusion that using autologous blood didn’t provide any additional benefits over saline for bone regeneration, which is relevant for oral and maxillofacial surgery.
