Profiles of preschoolers' numerical abilities across quantity representations.

Children's early numerical abilities shape their trajectories for math learning throughout schooling, and task quantity representation (e.g., nonsymbolic vs.

Design and Analytic Features for Reducing Biases in Skill-Building Intervention Impact Forecasts.

Despite policy relevance, longer-term evaluations of educational interventions are relatively rare. A common approach to this problem has been to rely on longitudinal research to determine targets for intervention by looking at the correlation between children's early skills (e.g.

Fewer boys born amid covid-19.

The initial stress of the pandemic may have skewed the birth sex ratio in England and Wales, possibly due to uncertainties causing pregnancy losses of male fetuses, finds .

Western Australia delays reopening.

The state has kept a tight lid on covid-19, but experts say there is little use holding out longer.

Predicting mathematics achievement from subdomains of early number competence: Differences by grade and achievement level.

This study investigated the relative importance of three subdomains of early number competence (number, number relations, and number operations) in predicting later mathematics achievement in cross-sequential samples of pre-kindergarten (pre-K), kindergarten, and first-grade children (n = 150 at each grade). Ordinary least-squares (OLS) regression analyses showed that each subdomain predicted mathematics achievement at each grade level, controlling for the other two subdomains as well as background variables. All the subdomains explained a significant amount of variance in later mathematics achievement.

New Zealand's new battle.

The return of covid-19 to the country after more than 100 days free of infections shows that nobody can relax, reports .

Novel polyamide amidine anthraquinone platinum(II) complexes: cytotoxicity, cellular accumulation, and fluorescence distributions in 2D and 3D cell culture models.

1- and 1,5-Aminoalkylamine substituted anthraquinones (AAQs, 1C3 and 1,5C3) were peptide coupled to 1-, 2-, and 3-pyrrole lexitropsins to generate compounds that incorporated both DNA minor groove and intercalating moieties. The corresponding platinum(II) amidine complexes were synthesized through a synthetically facile amine-to-platinum mediated nitrile 'Click' reaction. The precursors as well as the corresponding platinum(II) complexes were biologically evaluated in 2D monolayer cells and 3D tumour cell models.

Why we went for full elimination.

The doctor who devised New Zealand's early and extensive coronavirus response tells what inspired his successful strategy.

New Zealand's success.

The country is tantalisingly close to wiping out covid-19. Does that mean life there can go back to normal? reports.

Who will get ventilators in a covid-19 crisis?

If there is a shortage of breathing machines, doctors and ethicists say priority should go to people with the best chance of recovery, reports .

Drug trials under way.

We'll soon know if covid-19 can be treated with drugs developed for HIV and Ebola, reports .

How much bias results if a quasi-experimental design combines local comparison groups, a pretest outcome measure and other covariates?: A within study comparison of preschool effects.

This study uses a within study comparison design (WSC) to conduct a novel test of how much causal bias results when researchers use a nonequivalent comparison group design type (NECGD) that combines: (a) a comparison group local to the treatment group; (b) a pretest measure of the study outcome; and (c) a rich set of 19 other multidimensional covariates. Most prior WSCs have dealt with the bias consequences of only 1 of these, revealing that each routinely reduces bias but does not necessarily eliminate it. Thus, a need exists to identify NECGDs that more robustly eliminate bias.

Dimensionality of Preschoolers' Informal Mathematical Abilities.

Recent research examining children's early mathematical abilities has focused primarily on number and operations (e.g., counting, addition) with considerably less attention directed to the role of other possible dimensions of early mathematical abilities, such as, measurement, geometry, and patterning.

The Sequential Scale-Up of an Evidence-Based Intervention: A Case Study.

Policy makers face dilemmas when choosing a policy, program, or practice to implement. Researchers in education, public health, and other fields have proposed a sequential approach to identifying interventions worthy of broader adoption, involving pilot, efficacy, effectiveness, and scale-up studies. In this article, we examine a scale-up of an early math intervention to the state level, using a cluster randomized controlled trial.

Impacts of a Comprehensive School Readiness Curriculum for Preschool Children at Risk for Educational Difficulties.

This article reports findings from a cluster-randomized study of an integrated literacy- and math-focused preschool curriculum, comparing versions with and without an explicit socioemotional lesson component to a business-as-usual condition. Participants included 110 classroom teachers from randomized classrooms and approximately eight students from each classroom (N = 760) who averaged 4.48 (SD = 0.

The mechanisms underlying fructose-induced hypertension: a review.

We are currently in the midst of an epidemic of metabolic disorders, which may, in part, be explained by excess fructose intake. This theory is supported by epidemiological observations as well as experimental studies in animals and humans. Rising consumption of fructose has been matched with growing rates of hypertension, leading to concern from public health experts.

Enhancing early child care quality and learning for toddlers at risk: the responsive early childhood program.

Despite reports of positive effects of high-quality child care, few experimental studies have examined the process of improving low-quality center-based care for toddler-age children. In this article, we report intervention effects on child care teachers' behaviors and children's social, emotional, behavioral, early literacy, language, and math outcomes as well as the teacher-child relationship. The intervention targeted the use of a set of responsive teacher practices, derived from attachment and sociocultural theories, and a comprehensive curriculum.