Publications by authors named "Alice Einarsson"
Background: Whilst there is literature on the impact of SARS viruses in the severely immunosuppressed, less is known about the link between routine immunosuppressant use and outcome in COVID-19. Consequently, guidelines on their use vary depending on specific patient populations.
Methods: The study population was drawn from the COPE Study (COVID-19 in Older People), a multicentre observational cohort study, across the UK and Italy.
Objective: During the COVID-19 pandemic the continuation or cessation of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) has been contentious. Mechanisms have been proposed for both beneficial and detrimental effects. Recent studies have focused on mortality with no literature having examined length of hospital stay.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic has placed unprecedented strain on health-care systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the prevalence and effect of frailty in people with COVID-19 is not known. In the COVID-19 in Older PEople (COPE) study we aimed to establish the prevalence of frailty in patients with COVID-19 who were admitted to hospital and investigate its association with mortality and duration of hospital stay.
View Article and Find Full Text PDFArticle Synopsis
- Blood pressure variability (BPV) may be a risk factor for cardiovascular issues and mortality, but findings vary based on the population and measurement methods used.
- A systematic review analyzed 61 studies involving over 3.3 million individuals, focusing on short-term BPV measured over 24-hour periods or several days.
- Results indicated a moderate quality evidence linking BPV to cardiovascular events and all-cause mortality, while the association with cardiovascular mortality was less consistent across studies.