Background: Exemestane can prevent breast cancer in postmenopausal women. Because of potential widespread use, we examined the safety of exemestane on bone health.
Methods: In this nested safety substudy of the MAP.
Background: Although data from studies in animals demonstrated beneficial effects of whole-body vibration (WBV) therapy on bone, clinical trials in postmenopausal women showed conflicting results.
Objective: To determine whether WBV improves bone density and structure.
Design: A 12-month, single-center, superiority, randomized, controlled trial with 3 parallel groups.