Publications by authors named "Alice Bruynseels"
Material can be deposited in the cornea as a result of a wide range of systemic and ophthalmic diseases, as well as local and systemic therapies. Causes include local infection or trauma, systemic malignancy, a wide range of medications and a host of genetic and metabolic diseases. Some of these can be acutely life threatening, so generalists caring for both children and adults should have a basic awareness of the pattern and distribution of corneal deposits to facilitate timely diagnosis, investigation, management or onward referral to avoid significant morbidity or mortality.
View Article and Find Full Text PDFNystagmus is the repetitive to and fro movement of the eyes, which may be physiological or pathological. The movements can be horizontal, vertical, torsional or a combination of these movements. It starts by a slow movement of the eye away from the visual target.
View Article and Find Full Text PDFArticle Synopsis
- Deep learning algorithms show significant potential in medical diagnostics, prompting a systematic review to evaluate their accuracy against healthcare professionals in classifying diseases through medical imaging.
- From 31,587 studies screened, 82 met the criteria for inclusion, where sensitivity of deep learning methods ranged from 9.7% to 100% (mean 79.1%), and specificity ranged from 38.9% to 100% (mean 88.3%).
- In a subset of studies comparing deep learning with healthcare professionals, the pooled sensitivity for deep learning models was 87% compared to 86.4% for professionals, indicating comparable diagnostic performance.
Purpose: Self-care in chronic disease is increasingly important. In glaucoma services, there is an unmet need for a self-care tool such as a patient passport. This study aims to evaluate adoption of a new self-care tool, the Glaucoma Patient Passport (GPP) within a tertiary hospital glaucoma service.
View Article and Find Full Text PDFPurpose: Worldwide, as many as 6 million children annually sustain ocular trauma, with up to a quarter of a million children requiring hospitalization. Management of pediatric ocular trauma differs from that in adults, both in terms of initial assessment and acute intervention, with significant variation in practice between different centers. Patterns of healing and long-term outcomes are also very different for children compared to adults.
View Article and Find Full Text PDF: Patient self-care tools can improve patient outcomes in chronic disease. In uveitis, there is an unmet need for the innovative Uveitis Patient Passport (UPP). This study aims to evaluate the success of the passport's introduction into a tertiary uveitis service through patient experience.
View Article and Find Full Text PDFObjectives: To assess structural and functional outcomes of treatment with intravitreal aflibercept (Eylea) for diabetic macular oedema in treatment-naive patients.
Design: This is a retrospective, real-life, cohort study.
Participants And Methods: In all, 92 diabetic patients (102 eyes) receiving intravitreal anti-vascular endothelial growth factor therapy were included.
Objective: To investigate the effect of serum glycosylated hemoglobin (HbA1c) on the outcomes of ranibizumab therapy for diabetic macular edema (DME).
Design: Retrospective cohort study.
Participants: Patients receiving ranibizumab injections for centre-involving DME in a National Health Service setting.
Purpose: The purpose of this article was to describe (i) a novel case of severe intraocular pressure (IOP) elevation due to intracameral Healon 5 for management of early postoperative (post-op) hypotony following XEN Gel Stent insertion and (ii) the management of this complication.
Materials And Methods: A case report.
Results: A 52-year-old man, with primary open-angle glaucoma and suboptimal left IOP control on maximally tolerated medical therapy, was managed with XEN Gel Stent insertion at another tertiary eye unit.