Understanding of changes in salivary and lacrimal gland functions after radioactive iodine therapy (I-therapy) remains limited, and, to date, no studies have evaluated dose-response relationships between absorbed dose from I-therapy and dysfunctions of these glands. This study investigates salivary/lacrimal dysfunctions in differentiated thyroid cancer (DTC) patients six months after I-therapy, identifies I-therapy-related risk factors for salivary/lacrimal dysfunctions, and assesses the relationships between I-therapy radiation dose and these dysfunctions. A cohort study was conducted involving 136 DTC patients treated by I-therapy of whom 44 and 92 patients received 1.
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