The structure of tumors can be recapitulated as an elastic frame formed by the connected cytoskeletons of the cells invaded by interstitial and intracellular fluids. The low-frequency mechanics of this poroelastic system, dictated by the elastic skeleton only, control tumor growth, penetration of therapeutic agents, and invasiveness. The high-frequency mechanical properties containing the additional contribution of the internal fluids have also been posited to participate in tumor progression and drug resistance, but they remain largely unexplored.
View Article and Find Full Text PDFOur study proposes a new way to observe and explain the presence of extended plasmonic modes in disordered semi-continuous metal films before the percolation threshold. Attenuated total reflection spectroscopy allows us to follow the transition of plasmon modes from localized to delocalized resonances, but also reveals unobserved collective plasmon modes. These bright modes with out-of-plane polarization are transverse collective plasmonic resonances.
View Article and Find Full Text PDFThe acoustic vibrations of single monomers and dimers of gold nanoparticles were investigated by measuring for the first time their ultralow-frequency micro-Raman scattering. This experiment provides access not only to the frequency of the detected vibrational modes but also to their damping rate, which is obscured by inhomogeneous effects in measurements on ensembles of nano-objects. This allows a detailed analysis of the mechanical coupling occurring between two close nanoparticles (mediated by the polymer surrounding them) in the dimer case.
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