Comparative analysis of absorption resonances between carbynes and cyclo[n]carbons.

Two approaches are presented here to analyze the absorption resonances between carbynes and cyclo[n]carbons, namely the analytical tight-binding model to calculate the optical selection rules of cumulenic atomic rings and chains and thetime-dependent density functional theory for the optical investigation of polyynic carbon ring and chains. The optical absorption spectra of the carbon ring match that of the finite chain when their eigen energies align following theNring=2Nchain+2rule, which states that the number of atoms in an atomic ringNringis twice the number of atoms on a finite chainNchainwith two additional atoms. Two representative atomic chains are chosen for our numerical calculations, specifically carbynes withN=7and8carbon atoms as optical resonance spectra match to a recently synthesized carbon ring called cyclo[18]carbon.

Effect of the isotiazole adjuvants in combination with cisplatin in chemotherapy of neuroepithelial tumors: experimental results and modeling.

Chemotherapy is one of the main treatment options for cancer, but it is usually accompanied with negative side effects. The classical drugs combination with synergistic adjuvants can be the solution to this problem, allowing reducing therapeutic dose. Elucidating the mechanism of adjuvant action is of key importance for the selection of the optimal agent.