Propylthiouracil (PTU) is used to treat hyperthyroidism but can cause serious adverse reactions, particularly autoimmune conditions like lupus and vasculitis.
PTU-induced vasculitis is more common than lupus, often affecting the skin but can also involve organs like the kidneys and lungs, with risks of severe complications.
Discontinuing PTU usually leads to symptom resolution within a few weeks, but ongoing issues may require referral to a specialist for further treatment, particularly if symptoms persist after stopping the medication.