Publications by authors named "Aliakbar Ashkarran"
Article Synopsis
- Nanoparticles (NPs) interact with biomolecules in biological environments, forming a biomolecular corona (BC) that affects their biological identity and clinical applications.
- Understanding the BC’s true nature and its association with NPs is crucial for their safe and effective use in medicine.
- By using advanced imaging techniques like cryo-electron microscopy and tomography, researchers have visualized the unique structures and distributions of biomolecules around polystyrene NPs, improving NP characterization and safety predictions.
The adult myocardium has a limited regenerative capacity following heart injury, and the lost cells are primarily replaced by fibrotic scar tissue. Suboptimal efficiency of current clinical therapies to resurrect the infarcted heart results in injured heart enlargement and remodeling to maintain its physiological functions. These remodeling processes ultimately leads to ischemic cardiomyopathy and heart failure (HF).
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