Publications by authors named "Aliah R Alshanwani"
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Synopsis of recent research by authors named "Aliah R Alshanwani"
- Aliah R Alshanwani's recent research primarily focuses on the therapeutic effects of natural compounds, such as resveratrol and thymoquinone, in various disease models, highlighting their potential to modulate key signaling pathways implicated in cardiac remodeling, neurodegeneration, and attention-deficit/hyperactivity disorder (ADHD).
- Notably, the study on resveratrol-based liposomes demonstrated significant protection against isoproterenol-induced cardiac remodeling by modulating expressions of MEF2, Cytochrome C, and S100A1, while thymoquinone and thymol were shown to alleviate MSG-induced ADHD-like behavior in rats through the regulation of Nrf2/HO-1 and other inflammatory pathways.
- Additionally, Alshanwani has explored the molecular mechanisms underlying liver fibrosis and renal damage, revealing that compounds like pyridoxamine and chitosan nanoparticles may attenuate toxin-induced injuries by combating oxidative stress and regulating critical cellular pathways, indicating their potential as therapeutic agents in chronic liver diseases and nephrotoxicity.