Publications by authors named "Aliaa Gamaleldin Aboulela"
Statement Of Problem: Changes in the oral microbiota of new complete denture wearers are the main cause of oral candidiasis. The drawbacks associated with traditional antimycotic therapies, especially drug resistance, have led to the search for potent therapeutic and prophylaxis agents with less harmful effects, including probiotics. However, investigation of the prophylaxis and preventive effects of probiotics on new complete denture wearers are lacking.
View Article and Find Full Text PDFTreatment of Proteus mirabilis infections is a challenge due to the high abundance of virulence factors and the high intrinsic resistance to antimicrobials. Multidrug resistance (MDR) and extensive drug resistance (XDR) further challenge the control of P. mirabilis infection.
View Article and Find Full Text PDFPhytotherapeutics is widely used nowadays as an alternative to the current antifungal drugs to reduce their side effects. Curcumin, with its wide therapeutic array as antioxidant and anti-inflammatory agent, is one of the natural compounds that ha..
View Article and Find Full Text PDFArticle Synopsis
- Multidrug-resistant Klebsiella pneumoniae is a significant infectious pathogen, prompting researchers to analyze 39 isolates from nine hospitals in Egypt through whole-genome sequencing (WGS).
- The study identified various genetic factors associated with antibiotic resistance, finding 18 different sequence types, with ST101 and ST147 being the most prevalent, and detected multiple carbapenemase genes in many strains.
- Overall, the research highlights a concerning trend of international clones of MDR K. pneumoniae and their virulence traits in Egypt, similar to patterns observed globally, indicating a need for increased monitoring and response strategies.