Publications by authors named "Alia A Saleh"

Article Synopsis
  • - The study aimed to examine how Electroconvulsive Therapy (ECT) affects plasma BDNF levels in patients with resistant schizophrenia, comparing those who received ECT and those who continued with standard antipsychotic treatment.
  • - Results showed that patients receiving ECT had a significant increase in BDNF levels after treatment, while those on antipsychotics only had a non-significant increase; both groups experienced improvements in psychotic symptoms.
  • - The findings suggest that ECT can enhance plasma BDNF levels and promote clinical improvement in resistant schizophrenia, although BDNF levels did not correlate with the severity of symptoms.
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Background And Objectives: Montreal Cognitive Assessment-Basic (MoCA-B) is a modified version of the MoCA that is especially suitable for use in elderly subjects with low education. The Authors translated the tool into Arabic and they aimed at validation of this tool in a sample of elderly Egyptians.

Methods: The study included 93 patients, 60 years and older, fulfilling the DSM-5 criteria of Mild Neurocognitive Disorder (NCD) (39 patients) and Major Neurocognitive Disorder (54 patients) that were compared to 112 community dwelling elder subjects.

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Background: Research in bipolar disorder suggests the presence of structural brain abnormalities. It is not clear whether these findings are trait markers or operate with the onset and progress with disease severity and duration. Optical coherence tomography (OCT) is a non-invasive technique that detects degenerative changes in the retina reflecting brain degeneration.

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Background: There is an increased evidence of an association between inflammatory mediators, particularly serum IL-6, depression and cognitive impairment in the elderly. This study aims at exploring the relation of peripheral IL-6 to cognitive functions in elderly patients with major depressive disorder (MDD).

Objectives: (1) Assessment of serum IL-6 levels and cognitive functions in elderly patients suffering from major depression and comparing them to healthy age-matched control subjects; (2) correlation between serum IL-6 levels and clinical characteristics of depression and cognitive functions in these patients.

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