Publications by authors named "Ali-Rıza Atasoy"
Objective: Hepatitis C virus (HCV) infection is a major public health problem and affects large populations all over the world. Serum anti-HCV level is a valuable marker to determine HCV infection. Anti-HCV testing has been recommended for high-risk population.
View Article and Find Full Text PDFArticle Synopsis
- This study evaluated contamination rates in blood cultures across 16 hospitals, analyzing how various factors influenced results.
- The research involved 214,340 blood samples from over 43,000 patients, revealing that 33% of identified bacteria were contaminants, with coagulase-negative staphylococci being the most common.
- Findings suggest a need for improved training for hospital staff on blood collection methods to reduce contamination rates.
Investigation of OprD Porin Protein Levels in Carbapenem-Resistant Pseudomonas aeruginosa Isolates.
Jundishapur J Microbiol
December 2015
Article Synopsis
- OprD is a porin in Pseudomonas aeruginosa that allows the entry of basic amino acids and carbapenems; its resistance mechanisms include reduced expression and mutations.
- The study analyzed the expression levels of oprD in clinical isolates, revealing that most showed significant decreases in expression, particularly among multidrug-resistant strains.
- While decreased oprD levels are linked to carbapenem resistance, the study highlights that other mechanisms may also contribute to this resistance in addition to oprD expression.
Objectives: To evaluate the in vitro activity of doripenem in Acinetobacter baumannii (A. baumannii) clinical isolates that possess different OXA-type carbapenemases, and to evaluate the roles of these enzymes in the development of carbapenem resistance.
Methods: This retrospective study was conducted with 25 A.
Enzymatic modification of aminoglycosides by nucleotidyltransferases, acetyltransferases and/or phosphotransferases accounts for the majority of aminoglycoside-resistant Acinetobacter isolates. In this study, we investigated the relationship between aminoglycoside resistance and the presence of aminoglycoside-modifying enzymes in Acinetobacter baumannii clinical isolate groups with different resistance profiles. Thirty-two clinical A.
View Article and Find Full Text PDFBacteremia and sepsis are common causes of morbidity and mortality worldwide, with incorrect or delayed diagnoses being associated with increased mortality. New tests or markers that allow a more rapid and less costly detection of bacteremia and sepsis have been investigated. The aim of this study was to clarify the cutoff value of the neutrophillymphocyte ratio (NLR) according to procalcitonin (PCT) level in the decision-making processes for bacteremia and sepsis.
View Article and Find Full Text PDFAcinetobacter baumannii is the most important agent of nosocomial infections within the Acinetobacter genus. This gram-negative coccobacillus is intrinsically resistant to many antibiotics used in antimicrobial therapy, and capable of developing resistance including carbapenems. The objective of this study was to develop a multiplex real time polymerase chain reaction (qPCR) kit for OXA subgroups in A.
View Article and Find Full Text PDF