Minimally invasive surgery for placement of a subcutaneous EEG implant.

Background: A new class of subcutaneous electroencephalography has enabled ultra long-term monitoring of people with epilepsy. The objective of this paper is to describe surgeons' experiences in an early series of implantations as well as discomfort or complications experienced by the participants.

Methods: We included 38 implantation procedures from two trials on people with epilepsy and healthy adults.

EEG signatures of low back and knee joint pain during movement execution: a short report.

Chronic musculoskeletal pain has a high prevalence between European citizens, affecting their quality of life and their ability to work. The plastic changes associated with the occurrence of chronic musculoskeletal pain are still not fully understood. The current short report investigated the possible changes in brain activity caused by pain during movement in two of the most common musculoskeletal pain disorders in Denmark, knee pain and low back pain.

From pulse width modulated TENS to cortical modulation: based on EEG functional connectivity analysis.

Modulation in the temporal pattern of transcutaneous electrical nerve stimulation (TENS), such as Pulse width modulated (PWM), has been considered a new dimension in pain and neurorehabilitation therapy. Recently, the potentials of PWM TENS have been studied on sensory profiles and corticospinal activity. However, the underlying mechanism of PWM TENS on cortical network which might lead to pain alleviation is not yet investigated.

Alteration in Cortical Activity and Perceived Sensation Following Modulated TENS.

Over the last decades, conventional transcutaneous electrical nerve stimulation (TENS) has been utilized as an efficient rehabilitation intervention for alleviation of chronic pain, including phantom limb pain (PLP). However, recently the literature has increasingly focused on alternative temporal stimulation patterns such as pulse width modulation (PWM). While the effect of non-modulated high frequency (NMHF) TENS on somatosensory (SI) cortex activity and sensory perception has been studied, the possible alteration following PWM TENS at the SI has not yet been explored.

A simple and safe approach for simultaneous spectrophotometric determination of nitroglycerin and nitrocellulose in double base solid propellants.

An accurate, simple and safe method was developed for simultaneous determination of nitroglycerine (NG) and nitrocellulose (NC) in double base solid propellants (DB propellants). The proposed method is based on alkaline hydrolysis of NG and NC, and followed by colored reaction of released nitrite ion with p-nitroaniline in the presence of diphenylamine in acidic media and produce azo dye. The absorbance of the azo dye was measured at 534 nm.

Comparison of the effects of alcoholic extract of aerial parts of and atorvastatin on the lipid profile and thyroid hormones in hypercholesterolemic rats.

Objective: Decreased thyroid hormones along with increased blood fats and overweight, lead to atherosclerosis and eventually cardiovascular disease. The aim of this study was to compare the effects of alcoholic extract of aerial parts of and atorvastatin on the lipid profile and thyroid hormones in hypercholesterolemic rats.

Materials And Methods: In this study, 40 male Wistar rats were divided into 5 groups (n=8): control, hypercholesterolemic vehicle and three experimental groups.

Gamma-band enhancement of functional brain connectivity following transcutaneous electrical nerve stimulation.

Transcutaneous electrical nerve stimulation (TENS) has been suggested as a possible non-invasive pain treatment. However, the underlying mechanism of the analgesic effect of TENS and how brain network functional connectivity (FC) is affected following the use of TENS is not yet fully understood. The purpose of this study was to investigate the effect of high-frequency TENS on the alteration of functional brain network connectivity and the corresponding topographical changes, besides perceived sensations.

The physiological and pharmacological effects of L.: A review study.

Objective: Many reports have revealed preventive and therapeutic effects of ; however, few systematic reviews have evaluated such effects. The present study reviews the physiological and pharmacological effects of extract and its components.

Materials And Methods: English articles were searched in international databases, such as Embase, Scopus, and PubMed; Persian studies were also searched in national databases such as SID and Magiran.

Effect of Modulated TENS on Corticospinal Excitability in Healthy Subjects.

Conventional transcutaneous electrical nerve stimulation (TENS) has been reported to effectively alleviate chronic pain, including phantom limb pain (PLP). Recently, literature has focused on modulated TENS patterns, such as pulse width modulation (PWM) and burst modulation (BM), as alternatives to conventional, non-modulated (NM) sensory neurostimulation to increase the efficiency of rehabilitation. However, there is still limited knowledge of how these modulated TENS patterns affect corticospinal (CS) and motor cortex activity.

Metagenomics studies for the diagnosis and treatment of prostate cancer.

Aim: Mutation occurs in the prostate cell genes, leading to abnormal prostate proliferation and ultimately cancer. Prostate cancer (PC) is one of the most common cancers amongst men, and its prevalence worldwide increases relative to men's age. About 16% of the world's cancers are the result of microbes in the human body.

Investigating the demographic characteristics and pathological manifestations of thyroid Cancer during the last two decades (1997-2017) in patients referred to Baqiyatallah hospital, Tehran, Iran.

Background & Objective: Thyroid cancer is among the most common endocrine cancers, and its incidence in our country is in progress over the past decades. This aggravates the necessity to evaluate the changes in thyroid cancer.

Materials & Methods: Through accessing the information of the records of all patients with a diagnosis of thyroid cancer between 1996 and 2017, the present study was conducted at Baqiyatallah Hospital (Tehran, Iran) according to scientific criteria.

Short-Term Suppression of Somatosensory Evoked Potentials and Perceived Sensations in Healthy Subjects Following TENS.

Transcutaneous electrical nerve stimulation (TENS) has been reported to alleviate pain in chronic pain patients. Currently, there is limited knowledge how TENS affects can cause cortical neuromodulation and lead to modulation of non-painful and painful sensations. Our aim was therefore to investigate the effect of conventional, high-frequency TENS on cortical activation and perceived sensations in healthy subjects.

Transcutaneous Electrical Stimulation Influences the Time-Frequency Map of Cortical Activity - A Pilot Study.

Phantom limb pain (PLP) is pain felt in the missing limb in amputees. Somatosensory input delivered as high-frequency surface electrical stimulation may provoke a significant temporary decrease in PLP. Also, transcutaneous electrical nerve stimulation (TENS) is a somatosensory input that may activate descending inhibitory systems and thereby relieve pain.

The effect of hydro-alcoholic extract of on spermatogenesis index in rats treated with cyclophosphamide: An experimental study.

Background: The aim of this study was to investigate the antioxidant effects of extract on improving the toxicity induced by cyclophosphamide (CP) on spermatogenesis. 54 male Wistar rats (4 months old) weighing 200-250 gr were randomly divided into 6 groups (n = 9/each).

Objective: "group 1 (control) underwent the normal diet and water; group 2 (sham) received 2 ml/day normal saline; group 3 (positive control) received 300 mg/kg/day extract; group 4 received extract (300 mg/kg/day) + 5 mg/kg/day CP (Endoxan, baxter oncology gmbh, Germany) after 4 hr; group 5 (CP) received 5 mg/kg/day CP + normal saline 4 hr after it; and group 6 (CP + ) received extract (300 mg/kg/day) 4 hr after 5 mg/kg/day CP.

Miniaturized matrix solid-phase dispersion based on deep eutectic solvent and carbon nitride associated with high-performance liquid chromatography: A new feasibility for extraction and determination of trace nitrotoluene pollutants in soil samples.

In this research, a miniaturized version of matrix solid phase dispersion (MSPD) method was developed for successful extraction of five nitrotoluenes from soil samples. The terpene based deep eutectic solvent (DES) composed of borneol and DL-menthol was used simultaneously as extraction solvent and dispersing liquid. Graphitic-carbon nitride (g-CN) as sorbent was prepared by pyrolysis of melamine at a muffle furnace.

Creating cell and animal models of human disease by genome editing using CRISPR/Cas9.

A set of unique sequences in bacterial genomes, responsible for protecting bacteria against bacteriophages, has recently been used for the genetic manipulation of specific points in the genome. These systems consist of one RNA component and one enzyme component, known as CRISPR ("clustered regularly interspaced short palindromic repeats") and Cas9, respectively. The present review focuses on the applications of CRISPR/Cas9 technology in the development of cellular and animal models of human disease.

Ferrofluid of magnetic clay and menthol based deep eutectic solvent: Application in directly suspended droplet microextraction for enrichment of some emerging contaminant explosives in water and soil samples.

In this work, for the first time, ferrofluid of magnetic montmorillonite nanoclay and deep eutectic solvent was prepared and coupled with directly suspended droplet microextraction. Incorporation of ferrofluid in a miniaturized sample preparation technique resulted in achieving high extraction efficiency while developing a green analytical method. The prepared ferrofluid has strong sorbing properties and hydrophobic characteristics.

A new approach for separation and recovery of betaine from beet molasses based on cloud point extraction technique.

The aim of this work was to explore the possibility of the application of cloud point extraction (CPE) method in micelle media to recovery betaine from beet molasses. Response surface method was employed to assess the effects of surfactant concentration, molasses concentration, incubation time, pH, electrolyte concentration, mixing time, and surfactant type on efficiency of betaine recovery from beet molasses. Also, a mathematical model was developed to predict the effect of each variable and their interactions on the efficiency of betaine recovery.

Deep eutectic solvent based magnetic nanofluid in the development of stir bar sorptive dispersive microextraction: An efficient hyphenated sample preparation for ultra-trace nitroaromatic explosives extraction in wastewater.

A deep eutectic solvent based magnetic nanofluid was coupled with stir bar sorptive dispersive microextraction as a hyphenated sample preparation technique. The neodymium core magnetic stir bar was coated physically with nanofluid of magnetic carbon nanotube nanocomposites and deep eutectic solvents. The prepared nanofluid has magnetic and strong sorbing properties and is compatible with gas chromatography.

Degradation of nitro-aromatic explosives using recyclable magnetic photocatalyst: Catalyst synthesis and process optimization.

In this research, degradation of P-Nitrophenol (PNP) as a model nitro-aromatic compound was carried out by photocatalytic process using magnetic Titania nano particles (MTNPs). The recyclable MTNPs were synthesized with average diameter of 22nm and a narrow size distribution. The process was modeled and optimized by a second order reduced polynomial model.

Design and fabrication of optical chemical sensor for detection of nitroaromatic explosives based on fluorescence quenching of phenol red immobilized poly(vinyl alcohol) membrane.

The present study developed a new optical chemical sensor for detection of nitroaromatic explosives in liquid phase. The method is based on the fluorescence quenching of phenol red as fluorophore in a poly(vinyl alcohol) (PVA) membrane in the presence of nitroaromatic explosives as quenchers, e.g.

A quick overview on some aspects of endocrinological and therapeutic effects of Berberis vulgaris L.

Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry.

Prophylactic Effects of Lidocaine or Beclomethasone Spray on Post-Operative Sore Throat and Cough after Orotracheal Intubation.

Introduction: Post-operative sore throat and cough are common complications of endotracheal intubation. These conditions may be very distressing for the patient and may lead to unpleasant memories. This study was performed in order to determine whether beclomethasone and lidocaine spray could reduce the frequency of post-operative sore throat and hoarseness after tracheal extubation.

Hypoglycemic and hypolipidemic activities of Salvia hydrangea in streptozotocin-induced diabetes in rats.

Objectives: This study was to investigate the potential anti-diabetic effects of alcoholic extract of Salvia hydrangea in rats.

Materials And Methods: Thirty five male Wistar rats were divided into five groups namely non-diabetic control, diabetic control, and three experimental diabetic that received either Salvia hydrangea extract for 21 days at the doses of 100 and 200 or glibenclamide at the dose of 10 mg/kg through gavage feeding. To induce diabetes, streptozotocin was injected intraperitoneally.

Effects of ethanol extract of Salvia hydrangea on hepatic and renal functions of streptozotocin-induced diabetic rats.

Objectives: A wide range of liver and kidney disorders are associated with diabetes and there is a mutual relationship between diabetes and these diseases. Herbal medicine with having abundant ingredients is one of these options. The goal of this study was to compare the effects of alcoholic extract of aerial parts of S alvia hydrangea with glibenclamide on functional tests of liver and kidney in diabetic rats induced by streptozotocin.