Publications by authors named "Ali Vasheghani Farahani"
Objectives: Recent studies have suggested a potential link between opium consumption and microvascular dysfunction in coronary arteries, which may contribute to the development of coronary slow-flow syndrome. This study aims to investigate the relationship between opium use and coronary slow-flow syndrome.
Design And Setting: This retrospective study analysed medical records of patients who underwent coronary angiography at the Tehran Heart Center from 2006 to 2020.
Article Synopsis
- The Zika virus (ZIKV), an arbovirus from the Flavivirus genus, was first discovered in a monkey in Uganda in 1947 and has seen increasing prevalence, especially during a significant outbreak in the US in 2015 that caused severe health issues.
- Symptoms include organ failure, microcephaly, and Guillain-Barré syndrome, with the virus primarily transmitted through Aedes mosquitoes, but can also spread via blood, sexual contact, and from mothers to their babies.
- There's currently no specific treatment or vaccine for ZIKV, leading researchers to investigate its pathogenesis and clinical symptoms to improve understanding and develop future prevention and treatment strategies.
Prevalence and associated factors of ECG abnormality patterns indicative of cardiac channelopathies among adult general population of Tehran, Iran: a report from the Tehran Cohort Study (TeCS).
BMC Cardiovasc Disord
October 2024
Article Synopsis
- The study investigated ECG abnormalities related to cardiac channelopathies linked to sudden cardiac death among adults in Tehran, Iran, highlighting their under-recognition in the region.
- Out of 7,350 analyzed ECGs, long QT intervals were the most common abnormality found at 3.08%, with several factors influencing their prevalence, such as age and lifestyle choices.
- Overall, those with abnormal ECG patterns had a significantly higher all-cause mortality rate (6.3%) compared to those without such patterns (2.96%), indicating potential health risks.
Article Synopsis
- HPV is a virus that can cause cervical cancer and is a common STD that affects both guys and girls.
- A study in Mashhad, Iran tested 428 people for HPV and found that about 30% of them had the virus.
- The most common type of HPV found was HPV-6, and the study shows different types of HPV can affect people in different ways.
Triglyceride-glucose index as a predictor of cardiac adverse events in acute coronary syndrome patients undergoing percutaneous coronary intervention: role of diabetes.
BMC Cardiovasc Disord
September 2024
Article Synopsis
- The Triglyceride-glucose index (TyG) serves as a marker for insulin resistance and may predict the risk of major adverse cardiac and cerebrovascular events (MACCE) in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI).
- A study involving 13,542 patients showed that higher TyG levels, particularly in the fourth quartile, significantly correlated with an increased risk of MACCE, such as heart attacks and strokes.
- In contrast, no significant association was found between TyG levels and MACCE in a subgroup of patients who were euglycemic, suggesting the need for further studies to confirm these findings for better clinical risk assessment.
Article Synopsis
- * A significant portion of the cases (75%) were classified as high-risk, with HPV-11 and HPV-6 being the most frequently identified genotypes.
- * The findings highlight the urgent need for targeted education and vaccination efforts aimed at young individuals to combat the high rates of HPV infection, particularly focusing on high-risk strains.
Article Synopsis
- * A study from 1990 to 2019 revealed around 339,000 patients with AF/AFL in Iran, with 30,200 new cases and significant disability-adjusted life years (DALYs) lost, largely due to high blood pressure and body mass index.
- * Projections for 2050 indicate the number of AF/AFL patients could reach 1.1 million, emphasizing the need for improved prevention strategies targeting risk factors, despite advancements in treatment.
The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide. HEV is classified into eight genotypes, labeled HEV-1 through HEV-8. Genotypes 1 and 2 exclusively infect humans, while genotypes 3, 4, and 7 can infect both humans and animals.
View Article and Find Full Text PDFBackground: The prevalence of waterpipe smoking (WPS) has been increasing worldwide. This trend is alarming as WPS can negatively impact cardiovascular health. In the present study, we explored the association between WPS and the presence and severity of CAD.
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- Human papillomavirus (HPV) is a common sexually transmitted infection that can lead to various cancers, with this study focusing on its prevalence among women of different ages in Karaj.
- The research analyzed specimens from 2,109 women, finding that 17% tested positive for HPV, with a majority being low-risk, but a significant number also being high-risk, particularly in younger individuals under 30.
- The study identified HPV-16 as the most common genotype and emphasizes the importance of targeted health interventions and vaccination for specific age groups to reduce HPV-related risks.
Background: Extensive evidence has suggested the cardio-protective properties of the polyphenol curcumin. The aim of this study was to investigate the effects of a highly bioavailable curcumin supplement on cardiometabolic risk factors, health-related quality of life, and depression in patients with coronary slow flow phenomenon (CSFP).
Methods: This randomized double-blind placebo-controlled clinical trial was conducted in 42 patients with CSFP (age 35-70 years, 25 ≤ body mass index < 40 kg/m).
Purpose Of Review: Marital quality (MQ) is a psychosocial factor that has been neglected in cardiovascular prevention guidelines, although its association with cardiovascular diseases has been identified in several studies. Therefore, we aim to investigate how MQ either in positive or negative dimensions affect different cardiovascular risk factors and diseases.
Recent Findings: We systematically searched different databases in September 2023 for longitudinal studies conducted to assess the contribution of MQ to well-established cardiovascular risk factors and diseases.
Article Synopsis
- * The study found that higher rates of insufficient PA were particularly evident among females, older adults, the unemployed, housewives, and those with lower education levels, with additional correlations to higher body mass index and certain health conditions.
- * Logistic regression analysis showed that factors like older age, unemployment, and chronic conditions were significantly linked to a lack of sufficient PA, highlighting a need for targeted interventions in specific demographics.
Purpose: Obesity is a chronic low-grade inflammatory condition with increasing global prevalence and is associated with cardiovascular diseases. In this study, we aimed to investigate the prevalence of obesity in the Tehran cohort study (TeCS) population.
Methods: We used the data collected by systematic random sampling during the recruitment phase of TeCS.
Background: Cardiovascular events and poor quality of life are frequently observed in patients with coronary slow flow phenomenon (CSFP). This trial evaluated the effect of nano-curcumin supplement containing curcuminoids, as multifunctional nutraceuticals, on angina status, and some traditional and novel cardiovascular risk factors in overweight or obese patients with CSFP.
Methods: In this double-blind, randomized, placebo-controlled clinical trial, 42 overweight or obese patients with CSFP received either 80 mg/day of nano-curcumin or placebo for 12 weeks.
Article Synopsis
- Dyslipidemia is a major risk factor for cardiovascular diseases (CVDs) and is increasingly prevalent, particularly in developing nations; a study in Tehran assessed its prevalence and lipid profile abnormalities among adults aged 35 and older.
- Analysis of data from over 8,000 participants revealed an 82.7% prevalence rate of dyslipidemia, with specific issues like hypertriglyceridemia and low HDL-C also reported at significant rates and varying by geographic areas within Tehran.
- The findings underscore the urgent need for public health initiatives focused on preventing and managing dyslipidemia to mitigate health risks in the Tehran population.
Objectives: Using the cardiac surgery database is of high importance in referral centers and can lead to a better quality of care for patients. Tehran Heart Center (THC) is a cardiovascular referral center that was inaugurated in 2001. In this report, we aimed to present the third report of trends in patients' cardiovascular risk factors and surgical procedures from 2002 to 2021 that have been gathered for all THC patients.
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- - High-density lipoprotein cholesterol (HDL-C) is considered important for heart health, particularly regarding coronary artery diseases, but research on its influence on outcomes after coronary artery bypass graft (CABG) surgery is limited.
- - A study of 17,772 CABG patients from 2007 to 2017 found that low HDL-C levels did not correlate with increased mortality or major adverse cardiovascular events one year post-surgery after adjusting for confounding factors.
- - The analysis revealed that, while no significant overall association between HDL-C levels and outcomes was identified, a sex-based evaluation showed that higher HDL-C levels may offer more protective benefits for males after CABG.
Background: Unlike diabetes, the effect of prediabetes on outcomes in patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI) is not much investigated. We investigated the association between fasting glycemic status and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with ACS undergoing PCI and had mid to long-term follow-up after coronary stenting.
Methods: Registry-based retrospective cohort study included ACS patients who underwent PCI at the Tehran Heart Center from 2015 to 2021 with a median follow-up of 378 days.
Determining the recurrence rate of premature ventricular complexes and idiopathic ventricular tachycardia after radiofrequency catheter ablation with the help of designing a machine-learning model.
Regen Ther
December 2024
Ventricular arrhythmias increase cardiovascular morbidity and mortality. Recurrent PVCs and IVT are generally considered benign in the absence of structural heart abnormalities. Artificial intelligence is a rapidly growing field.
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- The study assessed the prevalence of substance and opium use among adult residents in Tehran, finding a 5.6% overall prevalence, with 95.8% of users favoring opium.
- It involved 8,259 participants and discovered that substance use was significantly more common in males (10.5% vs. 0.5% in females).
- The research identified male gender, alcohol intake, and smoking as key risk factors for opium use, suggesting that healthcare providers can use this data for preventive strategies.
Aim: A considerable proportion of patients admitted with acute coronary syndrome (ACS) have no standard modifiable cardiovascular risk factors (SMuRFs: hypertension, diabetes mellitus, dyslipidemia, and cigarette smoking). The outcomes of this population following percutaneous coronary intervention (PCI) are debated. Further, sex differences within this population have yet to be established.
View Article and Find Full Text PDFBackground: Recent changes in dietary habits have resulted in increased intake of advanced glycation end products (AGEs), which are known to have a predominant contribution to the pathogenesis and complications of coronary artery disease (CAD). AGEs are also thought to induce weight gain by affecting appetite, energy expenditure, and brown adipose tissue (BAT). Here, we investigated whether the restriction of dietary AGEs could affect appetite, body composition, anthropometric indices, and BAT-derived markers in CAD patients treated with angioplasty.
View Article and Find Full Text PDFBackground: Neuregulin-4 (Nrg4), a novel brown fat-enriched factor, has been reported to play a crucial role in developing metabolic disorders. The current case-control study aimed to investigate the association between serum Nrg4 and coronary artery disease (CAD).
Methods: This study enrolled 43 patients with CAD and 43 subjects with normal coronary arteries diagnosed by coronary angiography.