Identification of genetic biomarkers in urine for early detection of prostate cancer.

Prostate cancer screening is a challenging and vital issue in the aspects of the current tests and risk assessments. Prostate cancer risk assessments are currently carried out by using blood, urine and tissue biomarkers with radiological imaging methods. Here, we introduce a novel noninvasive screening tool for a further in-depth selection of eligible cases for prostate biopsies which is based on sequencing somatic and hereditary HOXB13 mutations in urine samples.

Does previous open nephrolithotomy affect the outcomes and complications of percutaneous nephrolithotomy in children?

Objective: To analyze the success and complication rates of percutaneous nephrolithotomy (PCNL) performed in pediatric patients and to compare outcomes of the patients undergoing primary PCNL with those of patients who had undergone previous open nephrolithotomy.

Materials And Methods: Between 2000 and 2011, PNL procedures were performed in 123 renal units (RU) of 111 children. We compared RU on which previous open surgery had been performed (group 1 RU = 26) on the same kidney with RU that had not been involved in previous surgery (group 2 RU = 97).

Percutaneous nephrolithotomy in children with cystine stone: long-term outcomes from a single institution.

Purpose: We determined the effectiveness of percutaneous nephrolithotomy in children with cystine stones and present the long-term outcomes.

Materials And Methods: We reviewed the data of 65 renal units in 51 children who underwent percutaneous nephrolithotomy for cystine stones between 2000 and 2012. Of the patients 19 (37%) had undergone ipsilateral renal surgery and 11 (22%) had undergone extracorporeal shock wave lithotripsy.

Case report: laparoscopically-treated giant renal hydatid cyst.

A 15 x 11 x 8-cm hydatid cyst in the right kidney of a 43-year-old man was treated using a laparoscopic approach. There was no preoperative or postoperative complications, and no recurrence was detected in 38 months of follow-up. This appears to be the first case of a renal hydatid cyst treated by a transperitoneal laparoscopic approach.

Assessment of the continence status and patients' satisfaction after retropubic radical prostatectomy: a questionnaire based study.

Objective: The aim of this study was to assess the continence status and patients' satisfaction after retropubic radical prostatectomy by a self-administered questionnaire composed of 12 questions.

Materials And Methods: In total, 143 patients who underwent RRP operation at our department from 1992 to 2000 with a minimum 6 months of follow-up were assessed. Seventy two patients participated in the study.

Pneumatic lithotripter application for giant bladder stone in a patient with augmentation cystoplasty.

An 18-year-old patient with repaired bladder exstrophy developed a 550-g stone burden in his augmented bladder. The stones were removed percutaneously with the aid of a pneumatic lithotripter. This should be considered the method of choice in these difficult cases.

Outcome of nephron-sparing surgery: elective versus imperative indications.

Introduction: The increase in the detection of renal tumors incidentally in earlier stages has enhanced the enthusiasm for nephron-sparing surgery (NSS).

Patients And Methods: We performed NSS in 76 patients (53 male, 23 female) with a mean age 52.3 between December 1988 and September 2001.

Transition zone biopsy and prediction of extraprostatic extension at radical prostatectomy.

Background: There is limited data in the literature that suggests that transition zone (TZ) biopsy might be useful for the prediction of extraprostatic extension (EPE) in clinically localized prostate cancer. We studied the role of TZ biopsy in the prediction of EPE.

Methods: Transition zone biopsies were performed in addition to systematic peripheral zone (PZ) biopsies between November 1995 and December 1999.

Is periprostatic local anesthesia for transrectal ultrasound guided prostate biopsy associated with increased infectious or hemorrhagic complications? A prospective randomized trial.

Purpose: Periprostatic local anesthesia for prostate biopsy requires 2 or more extra needle punctures and injection of the local anesthetic through the highly colonized rectum. To our knowledge we report the first prospective randomized trial to assess the infectious or hemorrhagic complications associated with this method.

Materials And Methods: A total of 100 consecutive patients with sterile urine cultures underwent transrectal ultrasound guided prostate biopsy.