Publications by authors named "Ali Tahri"
Risk factors for inflammatory and non-inflammatory breast cancer in North Africa.
Breast Cancer Res Treat
November 2020
Article Synopsis
- The study investigated various risk factors associated with inflammatory breast cancer (IBC) through a case-control analysis involving 267 IBC cases alongside matched non-IBC cases and controls across Egypt, Tunisia, and Morocco.
- Findings indicated that a recent livebirth and diabetes were linked to an increased risk of IBC, while certain factors such as family history of breast cancer and low socioeconomic status elevated the risk for both IBC and non-IBC.
- The research highlights potential new risk factors for IBC, suggesting that confirming these associations could improve understanding and prevention of this aggressive cancer type.
Article Synopsis
- - The study analyzed the clinico-pathologic and mammographic features of 267 inflammatory breast cancer (IBC) cases and 274 matched non-IBC cases across Egypt, Tunisia, and Morocco from 2009 to 2015, emphasizing the subjective nature of IBC diagnosis based on clinical signs like erythema.
- - Results revealed significant differences between IBC and non-IBC cases, including hormone receptor status, presence of erythema, and mammographic findings, with higher percentages of IBC patients meeting expert definitions of the condition.
- - The findings suggest that using standardized medical photographs and expert reviews is crucial to improve the reliability of IBC diagnoses, highlighting the need for clear clinical guidelines in identifying this aggressive cancer type
Article Synopsis
- Idiopathic granulomatous mastitis (IGM) is a chronic breast inflammatory condition with unknown causes, and it varies in symptoms and treatment approaches due to its complexity.
- IgG4-related disease (IgG4-RD) is a newly identified systemic condition that can mimic IGM, characterized by specific histological features and typically treated with immunosuppressive therapy.
- The researchers developed the Michigan Classification system to differentiate between IGM and IgG4-RD mastitis, analyzing 43 cases and identifying 17 cases of IgG4-RD and 8 of IGM, with the classification aiding in patient treatment strategies.
Gastric cancer is the fifth most common cancer globally with over 70% of new cases occurring in developing countries. In Morocco, oncologists in Marrakech suspected higher frequency of gastric cancer compared to Casablanca, a city 150 kilometers away. This study calculated age-specific, sex-specific, and total incidence rates of gastric cancer in Marrakech and was compared to the Casablanca population-based cancer registry.
View Article and Find Full Text PDFChronic mastitis is a prolonged inflammatory breast disease, and little is known about its etiology. We identified 85 cases and 112 controls from 5 hospitals in Morocco and Egypt. Cases were women with chronic mastitis (including periductal, lobular, granulomatous, lymphocytic, and duct ectasia with mastitis).
View Article and Find Full Text PDFMetastatic breast cancer (MBC) is an incurable disease. The goal of treatment is mainly palliative to improve quality of life by the control of disease (in terms of disease free survival [DFS]) as long as possible, and to treat symptoms with fewer side effects. The gene c-erb B2 or neu or HER2 is amplified in 20-25% of breast cancers.
View Article and Find Full Text PDFBackground: The HER2 gene or c-erb B2 or neu is amplified in 15-25% of breast cancers. This amplification is associated with an aggressive course of disease. The trastuzumab is a monoclonal antibody targeting the extracellular domain of HER2.
View Article and Find Full Text PDFIn the Congress of European Cancer Organisation (ECCO)/European Society for Medical Oncology (ESMO), which took place in Stockholm between 23 and 27 September 2011, urological cancers were the subject of various oral presentations and posters. A selection of the more innovative researches, likely to change the patients' management was performed. In prostate cancer, abiraterone acetate should be indicated in patients previously treated with docetaxel and sipuleucel-T in patients with asymptomatic or minimally symptomatic castrate-resistant prostate cancer.
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