A facile synthesis of iron oxide nanoparticles as a nano-sensor to detect levofloxacin and ciprofloxacin in human blood and evaluation of their biological activities.

A rapid synthesis of a pH-stable magnetic nano-sensor (iron oxide nanoparticles, Fe-NPs, ∼2.6 nm) encapsulated with 3-aminobenzoic acid (3-ABA) was achieved. 3-ABA was prepared for the first time through the reduction of 3-nitrobenzoic acid (3-NBA) in the presence of HCl and tin.

Synthesis, Characterization, DPPH Radical Scavenging, Urease Enzyme Inhibition, Molecular Docking Simulation, and DFT Analysis of Imine Derivatives of 4-formylpyridine with Selective Detection of Cu+2 Ions.

This study aimed to prepare three imine derivatives (1, 2, and 3) via a condensation reaction of phenyl hydrazine, 2-hydrazino pyridine, and 4-methoxy aniline with 4-formyl pyridine. Electron impact mass spectrometry (EIMS), proton nuclear magnetic resonance (1H-NMR), ultraviolet-visible (UV-Vis) and Fourier transform infrared (FTIR) spectroscopy were utilized for the characterization. The chemosensing properties of [4((2-phenyl hydrazono)methyl) pyridine] (1), [2-(2-(pyridin-4-ylmethylene)hydrazinyl) pyridine] (2), and [4-methoxy-N-yl methylene) aniline] (3) imino bases have been explored for the first time in aqueous media.

An efficient synthesis of and alkyl derivatives of 4-aminobenzoic acid and evaluation of their anticancer properties.

A series of twenty alkyl derivatives () of 4-amino benzoic acid (, PABA) have been prepared using potassium carbonate and opportune alkylating agents under simple and mild reaction conditions. Compounds () are reported for the first time. Electron impact mass spectrometry (EIMS), Fourier transform infrared (FTIR) and Proton nuclear magnetic resonance (H-NMR) spectroscopic techniques were adopted for the characterization of these analogues.

Analysis of the Antimicrobial and Anti-Biofilm Activity of Natural Compounds and Their Analogues against Isolates.

(1) Background: Staphylococcus aureus (S. aureus) is one of the most frequent causes of biofilm-associated infections. With the emergence of antibiotic-resistant, especially methicillin-resistant S.

Volatile constituents and in vitro activity of Syzygium aromaticum flower buds (clove) against human cancer cell lines.

The methanolic extract (SA-EXT) of Syzygium aromaticum flower buds and its fractions tested against three human cancer cell lines viz uterine cervix (HeLa), breast (MCF-7) and lung NCI (H-460) using sulforhodamine-B assay. The ethyl acetate soluble sub fraction (SA-EAS) was active only against HeLa cells with GIvalue of 36± 3.4μg/mL.

Triterpenoids from the aerial parts of Lantana camara.

Two new pentacyclic triterpenoids lancamarinic acid and lancamarinin have been obtained from the aerial parts of Lantana camara Linn. They were characterized as 22β-acetoxy-3,25-epoxy-3α-hydroxyolean-12-en-28-oic acid and methyl 3,25-epoxy-3α-hydroxy-11-oxo-22β-senecioyloxyolean-12-en-28-oate, respectively, through chemical transformation and exhaustive spectroscopic studies.

Analgesic and anti-inflammatory activities of Piper nigrum L.

Objective: To evaluate and compare the analgesic and anti-inflammatory activity of pure compound, piperine along with hexane and ethanol extracts of Piper nigrum L. fruit in mice and rats.

Methods: The analgesic activity was determined by tail immersion method, analgesy-meter, hot plate and acetic acid induced writhing test.

Synthesis and preparation of fluorinated polycarbonates enhancing the light absorption of fluorescent nanoparticles.

A new synthetic method for fluorinated polycarbonates without the use of any toxic phosgene gas is presented. The synthesis consists of a monomer synthesis followed by polymerization. The fluorinated polycarbonate (FPC) was confirmed by Fourier transform infrared spectroscopy (FT-IR) and NMR spectroscopy.

An efficient, mild and solvent-free synthesis of benzene ring acylated harmalines.

A facile synthesis of a series of benzene ring acylated analogues of harmaline has been achieved by Friedel-Crafts acylation under solvent-free conditions at room temperature using acyl halides/acid anhydrides and AlCl3. The reaction afforded 10- and 12-acyl analogues of harmaline in good yield, along with minor quantities of N-acyl-tryptamines and 8-acyl analogues of N-acyltryptamines.

3-Methyl-1H-pyrrolo[2,1-c][1,4]oxazin-1-one.

In the title mol-ecule, C(8)H(7)NO(2), all the non-H atoms lie essentially in the same plane (r.m.s.

Di-tert-butyl cyclo-hex-2-ene-1,4-diyl dicarbonate.

In the title mol-ecule, C(16)H(26)O(6), the central cyclo-hexene ring is in a half-chair conformation. The carbonyl groups are in a trans arrangement with respect to each other and the dihedral angle between the mean planes of the carbonate groups is 10.8 (2)°.

A new ethylene glycol triterpenoid from the leaves of Psidium guajava.

One new pentacyclic triterpenoid psidiumoic acid (5) along with four known compounds beta-sitosterol (1), obtusol (2), oleanolic acid (3), and ursolic acid (4) have been isolated from the leaves of Psidium guajava. The new constituent 5 has been characterized as 2 alpha-glycolyl-3beta-hydroxyolean-12-en-28-oic acid through 2D NMR techniques. This is the first report of isolation of compound 2 from the genus Psidium.

Chemical constituents from the leaves of Psidium guajava.

Five constituents including one new pentacyclic triterpenoid guajanoic acid (1) and four known compounds beta-sitosterol (2), uvaol (3), oleanolic acid (4), and ursolic acid (5) have been isolated from the leaves of Psidium guajava. The new constituent 1 has been characterized as 3beta-p-E-coumaroyloxy-2alpha-methoxyurs-12-en-28-oic acid through 2D NMR techniques and chemical transformations. This is the first report of isolation of compound 3 from the genus Psidium.