Breast cancer is a common form of cancer among women characterized by the growth of malignant cells in the breast tissue. The most common treatments for this condition include chemotherapy, surgical intervention, radiation therapy, hormone therapy, and biological therapy. The primary issues associated with chemotherapy and radiation therapy are their adverse events and significant financial burden among patients in underdeveloped countries.
View Article and Find Full Text PDFThis mini-review analyzed two approaches to screening bacterial contamination and utilizing pathogen reduction technology (PRT) for Platelet concentrates (PCs). While the culture-based method is still considered the gold standard for detecting bacterial contamination in PCs, efforts in the past two decades to minimize transfusion-transmitted bacterial infections (TTBIs) have been insufficient to eliminate this infectious threat. PRTs have emerged as a crucial tool to enhance safety and mitigate these risks.
View Article and Find Full Text PDFExosomes are small membrane vesicles of endocytic origin that are produced by both tumor and normal cells and can be found in physiological fluids like plasma and cell culture supernatants. They include cytokines, growth factors, proteins, lipids, RNAs, and metabolites and are important intercellular communication controllers in several disorders. According to a vast amount of research, exosomes could support or inhibit tumor start and diffusion in a variety of solid and hematological malignancies by paracrine signaling.
View Article and Find Full Text PDFNanoparticles have demonstrated noteworthy advancements in the management of various complex medical conditions, particularly cancer. In any case, these particles still harbor the potential to improve medicate conveyance to challenging, hard-to-reach loci. The interactions that occur between nanoparticles and red blood cells during their journey throughout the human body, despite exposure to blood, are still not fully understood.
View Article and Find Full Text PDFThe novel coronavirus infection (COVID-19) conveys a serious global threat to health and economy. A common predisposing factor for development to serious progressive disease is presence of a low-grade inflammation, e.g.
View Article and Find Full Text PDFNanotechnology mainly deals with the production and application of compounds with dimensions in nanoscale. Given their dimensions, these materials have considerable surface/volume ratios, and hence, specific characteristics. Nowadays, environmentally friendly procedures are being proposed for fabrication of Fe nanoparticles because a large amount of poisonous chemicals and unfavorable conditions are needed to prepare them.
View Article and Find Full Text PDFThe renewable, proteinaceous, marine biopolymer spongin is yet the focus of modern research. The preparation of a magnetic three-dimensional (3D) spongin scaffold with nano-sized FeO cores is reported here for the first time. The formation of this magnetic spongin-FeO composite was characterized by X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential thermal analysis (DTA) (TGA-DTA), vibrating sample magnetometer (VSM), Fourier-transform infrared spectroscopy (FTIR), and zeta potential analyses.
View Article and Find Full Text PDFPreparing samples for analyses is perhaps the most important part to analyses. The varied functional groups present on the surface of biopolymers bestow them appropriate adsorption properties. Properties like biocompatibility, biodegradability, presence of different surface functional group, high porosity, considerable absorption capacity for water, the potential for modification, etc.
View Article and Find Full Text PDFWith the development of nanomaterials in electrochemical sensors, the use of nanostructures to modify the electrode surface has been shown to improve the kinetics of the electron transfer process. In this study, a sensor was developed for the electrochemical determination of Acyclovir (ACV) based on the modified carbon paste electrode (CPE) by CdO/FeO. The magnetic CdO nanoparticles characterization was studied by energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD).
View Article and Find Full Text PDFTo promote the low photocatalytic efficiency caused by the recombination of electron/hole pairs and widen the photo-response wavelength window, ZnFeO@ZnO-N/B/RGO and ZnFeO@ZnO-CN ternary heterojunction nanophotocatalysts were designed and successfully prepared through a sol-gel technique. In comparison to bare ZnFeO and ZnO, the ZnFeO-ZnO@N/B/RGO and ZnFeO@ZnO-CN ternary products showed highly improved photocatalytic properties in the degradation of methyl orange (MO) under ultra-violet (UV) and visible light irradiation. Various physicochemical properties of the photocatalysts were evaluated through field emission scanning electron microscopy (FESEM), energy-dispersive X-ray (EDX) analysis, X-ray diffraction (XRD), UV-visible diffuse reflectance spectroscopy (DRS), Fourier transform infrared spectroscopy (FT-IR), and vibrating sample magnetometer (VSM) techniques.
View Article and Find Full Text PDFFront Pharmacol
March 2020
The new nanocomposite with various molar ratios along with magnetic properties was fabricated precipitation (assisted by ultrasonic) procedure. The photocatalytic effects of methylene blue (∼90% degradation for optimized sample in 100 min) for finding the optimized sample performed under visible light irradiation. Moreover, the photo-antibacterial impacts of bacteria culture environments were found with an optimized sample that had effective destruction of bacteria in comparison to control group.
View Article and Find Full Text PDFA nanostructure was prepared from titania nanoparticles and copper oxide (TiONP@CuO) and used to modify a carbon paste electrode (CPE). The modified CPE is shown to enable sensitive voltammetric determination of the drug clozapine (CLZ). The sensor was characterized by various techniques and some key parameters were optimized.
View Article and Find Full Text PDFFeO/CdWO and FeO/CdWO/PrVO magnetic nanoparticles were prepared at different molar ratios of PrVO to previous layers (FeO/CdWO) via the co-precipitation method assisted by a sonochemical procedure, in order to investigate the photocatalytic performance of these systems and their cytotoxicity properties. The physico-chemical properties of these magnetic nanoparticles were determined via several experimental methods: X-ray diffraction, energy dispersive X-ray spectroscopy, Fourier transformation infrared spectroscopy and ultraviolet-visible diffuse reflection spectroscopy, using a vibrating sample magnetometer and a scanning electron microscope. The average sizes of these nanoparticles were found to be in the range of 60-100 nm.
View Article and Find Full Text PDFThe aim of the present study is to develop a simple and convenient co-precipitation method to synthesize Mn(VO₃)₂ nanorods with the aid of polysorbate as the polymeric capping agent in an aqueous environment. The energy-dispersive X-ray spectroscopy, X-ray diffraction, scanning electron microscopy, diffuse reflectance spectroscopy, and vibrating-sample magnetometer techniques were applied to characterize chemical structure, morphology, and optical properties of nanorods. According to the XRD and SEM results, various polysorbate has direct impact on the morphology and crystal size.
View Article and Find Full Text PDFHere, a specific and reliable fluorometric method for the rapid determination of amikacin was developed based on the molecularly imprinting polymer (MIP) capped g-CN quantum dots (QDs). g-CN QDs were obtained by facile and one-spot ethanol-thermal treatment of bulk g-CN powder and showed a high yield fluorescence emission under UV irradiation. The MIP layer was also created on the surface on QDs, via usual self-assembly process of 3-aminopropyl triethoxysilane (APTES) functional monomers and tetraethyl ortho-silicate (TEOS) cross linker in the presence of amikacin as template molecules.
View Article and Find Full Text PDFThulium titanate/polyaniline nanocomposites were synthesized to observe the sonophotocatalytic degradation of dyes (widely used as a model pollutant) under ultrasonic irradiation and visible light. Based on our results, the synthesis process can improve sol-gel assisted sonochemical method in the presence of ultrasound and starch. To prepare pure thulium titanate nanostructures, the presence of starch and sonication treatment were concurrently obligatory.
View Article and Find Full Text PDFSonochemically prepared nanoparticles of terbium tungstate (TWNPs) were evaluated through scanning electron microscopy (SEM), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR), UV-Vis spectroscopy, and the optimal products were further characterized in terms of their electrochemical properties using conventional and continuous cyclic voltammetry (CV, and CCV), galvanostatic charge/discharge technique, and electrochemical impedance spectroscopy (EIS). The CV studies indicated the TWNPs to have specific capacitance (SC) values of 336 and 205 F g at 1 and 200 mV s, and galvanostatic charge-discharge tests revealed the SC of the TWNP-based electrodes to be 300 F g at 1 Ag. Also continuous cyclic voltammetry evaluations proved the sample as having a capacitance retention value of 95.
View Article and Find Full Text PDFYbVO nanostructure and YbVO/CuWO nanocomposites were successfully synthesized using sonochemical method, for the first time. In this disquisition, we tried to compare various parameters and reaction conditions on size, morphology, and uniformity of as-obtained samples. To reach optimum condition, some parameters including time, power, temperature, and solvent were investigated.
View Article and Find Full Text PDFIn this work, a label-free electrochemical immunosensor was constructed on the base of poly p-phenylenediamine (PPD) and GR nanocomposite (PPD-GR). Screen-printed electrodes modified with PPD-GR nanocomposite and applied to advance enzyme-free and label free electrochemical immunosensor for detection of protein biomarker neuron-specific enolase (NSE). It was found that the PPD-GR nanocomposite exhibits excellent electrocatalytic activity towards ascorbic acid (AA) oxidation as analytical signal based on EC' mechanism.
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