Effects of general and spinal anesthetic techniques on endothelial adhesion molecules in cesarean section.

Background: The aim of this study was to investigate the effects of anesthetic techniques used during general anesthesia (GA) and spinal anesthesia (SA) on endothelial adhesion molecules in the fetal circulation of healthy parturients undergoing elective cesarean section.

Methods: Patients were randomly assigned to either the general anesthesia (n = 20) or spinal anesthesia (n = 20) group. Maternal and cord blood neopterin, sE-selectin, and sL-selectin levels were measured in both groups.

A new treatment modality for unilateral athelectasis: Recruitment maneuver with endobronchial blocker.

Atelectasis is a commonly seen complication during the post-operative period in intensive care units. The treatment of atelectasis depends on the underlying cause. We aimed to share our experience on the treatment of right total atelectasis in our intensive care unit applied with the help of the endobronchial blocker.

Effects of the menstrual cycle on injection pain due to rocuronium.

Study Objective: To investigate the effect of the menstrual cycle on rocuronium injection pain.

Design: Prospective, randomized, double-blinded study.

Setting: Academic medical center.

[A comparison of the efficacy of bupivacaine and levobupivacaine in patient-controlled epidural analgesia for postoperative pain in patients undergoing knee arthroplasty].

Objectives: In this study, we aimed to compare the efficacy of bupivacaine and levobupivacaine in the patient-controlled epidural analgesia (PCEA) in patients who underwent total knee arthroplasty (TKA), particularly with cardiac diseases.

Patients And Methods: Forty-four patients (16 males, 28 females; mean age 70.2±6.

A novel treatment of chronic orchialgia.

We evaluated the effectiveness of pulsed radiofrequency (PRF) denervation of spermatic cord for the treatment of chronic orchialgia. Five patients diagnosed with chronic orchialgia were evaluated with a thorough medical and psychiatric history, physical examination, and scrotal Doppler ultrasound, urinary system x-ray film, and urine analyses. One of the patients had bilateral chronic orchialgia.

Dexmedetomidine: an alternative for epidural anesthesia in tension-free vaginal-tape surgery.

Purpose: Anesthetic management of tension-free vaginal-tape (TVT) procedures is sometimes difficult to deal with, especially when surgeons request a cough test. Dexmedetomidine has unique sedative and analgesic properties while having minimal respiratory effects, making it suitable for perioperative use in monitored anesthesia care. We aimed to compare dexmedetomidine and epidural anesthesia in TVT patients.

Efficacy of different concentrations of sevoflurane administered through a face mask for magnetic resonance imaging in children.

Background: The main aim of this study was to use a non-invasive method such as a face mask to maintain anesthesia in children during magnetic resonance imaging (MRI). The secondary aim was to ascertain hemodynamic-respiration parameters, recovery time and complications of anesthesia with the administration of different concentrations of sevoflurane.

Methods: This prospective and randomized study included 96 ASA I-II children, aged 1-10, scheduled to undergo MRI with anesthesia with sevoflurane through a face mask.

The efficiency and duration of the analgesic effects of musical therapy on postoperative pain.

Objectives: The aim of this study was first to find out the effect of music therapy on postoperative analgesia and second to determine the duration of its effect.

Methods: Seventy patients who were undergoing elective cesarean delivery were enrolled. The patients were randomly allocated into two groups as follows: In Group 1, patients listened to music through a headphone for one hour after surgery, while in Group 2, patients did not listen to any music during the same period.

Pressure-controlled vs volume-controlled ventilation during laparoscopic gynecologic surgery.

Study Objective: To quantify and compare the effects of conventional volume-controlled ventilation (VCV) with the alternative mode, pressure-controlled ventilation (PCV), on respiratory mechanics and noninvasive hemodynamic parameters in patients undergoing laparoscopic gynecologic surgery.

Design: Randomized controlled trial (Canadian Task Force classification I).

Setting: Respiratory mechanics and hemodynamic parameters were recorded for each patient at time T1, 10 minutes after induction, in the supine position; T2, 15 minutes after pneumoperitoneum, in the Trendelenburg position; and T3, 10 minutes after pneumoperitoneum withdrawal, in the supine position.

Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways.

Background: Tramadol is an analgesic drug, and its mechanism of action is believed to be mediated by the mu-opioid receptor. A further action of tramadol has been identified as blocking the reuptake of serotonin (5-HT). One of the most recently identified subtypes of 5-HT receptor is the 5-HT7 receptor.

[A clinic's experiences in postoperative patient controlled analgesia].

Objectives: Postoperative analgesia technique varies depending on the operation, patient, anesthetist, and circumstances. PCA (patient controlled analgesia) is an effective way of supporting postoperative analgesia. In this study, we aimed to present the efficacy and safety of our postoperative PCA treatment and the patient profile along with the requirements, preferences and decision-making process.

A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.

Background: Gabapentin and ketamine are popular analgesic adjuvants for improving perioperative pain management. We designed this double-blind, placebo-controlled study to test and compare the preventive effects of perioperative ketamine and gabapentin on early and chronic pain after elective hysterectomy.

Methods: Sixty patients undergoing abdominal hysterectomy were randomly assigned to 1 of the following 3 groups: control group received oral placebo capsules and bolus plus infusion of saline; ketamine group received oral placebo capsules and, before incision, 0.

Unexpected difficult intubation due to lingual tonsillar hyperplasia in a thoracotomy patient: intubation with the double-lumen tube using stylet and fiberoptic bronchoscopy.

Lingual tonsillar hyperplasia is rare, and it may cause difficulty with tracheal intubation during induction of general anesthesia. A different orotracheal intubation technique was performed using a double-lumen endotracheal tube, flexible fiberoptic bronchoscope, and a stylet, in an unexpected difficult endobronchial intubation case due to massive lingual tonsillar hyperplasia.

The effects of gabapentin on acute and chronic pain after inguinal herniorrhaphy.

Background And Objective: To find out whether preoperative gabapentin use had a favourable effect on long-term postoperative pain in patients undergoing inguinal herniorrhaphy.

Methods: Sixty male patients--aged 20-40 years--who were scheduled for unilateral inguinal herniorrhaphy under spinal anaesthesia were included in this prospective, randomized, double-blind study. The patients were randomly allocated to two groups: the gabapentin group (n=30) received single-dose 1.

Proanthocyanidin protects intestine and remote organs against mesenteric ischemia/reperfusion injury.

Background: Intestinal ischemia/reperfusion (IR) induces a systemic inflammatory response and releases harmful substances that may affect the function and integrity of distant organs such as lung, liver, and kidney. We conducted this study to find out if proanthocyanidins (PA) has protective effects against mesenteric IR injury and mesenteric IR-induced intestinal and distant organ injury.

Materials And Methods: Thirty-two Sprague-Dawley rats were divided into four groups: control, control + PA, IR, IR + PA.

Ameliorative effects of proanthocyanidin on renal ischemia/reperfusion injury.

Introduction: Several natural products have been reported to have beneficial effects on ischemia/reperfusion (I/R) injury, particularly from a preventative perspective. Therefore, this study was designed to investigate the efficiency of proanthocyanidin (PA), a natural product derived from grape seed, on renal dysfunction and injury induced by I/R of rat kidney.

Materials And Methods: Twenty-four male Sprague-Dawley rats were divided into three groups: sham-operated, I/R, I/R+PA.

Blood pressure changes in young male subjects exposed to a median altitude.

Objective: Residence at high altitude has been associated with elevation in systemic blood pressure (BP), but few studies have been done on the time course and the effects of a median altitude. Moreover, there exist population differences in the reactions given to altitude and the mechanism is unknown. This study was therefore designed to determine the effects of a median altitude on resting BP and heart rate (HR) in a group of 15 healthy, young, Turkish male subjects.

Accuracy of caudal epidural injection: the importance of real-time imaging.

Caudal epidural steroid injections are often used for low back pain. Fluoroscopic guidance has been frequently cited as a requirement for this procedure. In this preliminary report, we demonstrate that fluoroscopic guidance for caudal epidural Tuohy needle placement without real-time imaging may result in inadvertent intravenous injection of the drug.

Hearing impairment associated with spinal anesthesia.

Objectives: Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation.

Material And Methods: The effect of spinal needle diameter on hearing loss was investigated using audiometric tests in a prospective comparative study of 30 patients who were scheduled for surgery with spinal anesthesia.

The use of the corpus cavernosum for the administration of phenobarbital: an experimental study in dogs.

Status epilepticus (SE) is classically defined as a generalized tonic-clonic seizure lasting longer than 30 min. Prolonged seizure activity can be resulted in irreversible cerebral injury. In addition, the existence evidence suggests that the longer the duration of the seizure activity is less likely to be controlled.

Intracavernous application of diazepam: an alternative route of the seizure treatment--an experimental study in rabbits.

Background: There is a general need to terminate seizures as soon as possible using anticonvulsant drugs via an intravenous (i.v.) route, but it is often difficult to achieve a secure i.