DNA topoisomerase 2 gene polymorphism in dermatophytes.

Background: Dermatophytes are a group of keratinophilic fungi of medical importance. Despite a relatively long history of molecular taxonomic studies, there is still a need for information on genetic polymorphism in wider variety of genomic loci.

Objectives: Our goal was to study partial DNA topoisomerase 2 gene (TOP2) polymorphism in dermatophytes.

Emergence of Terbinafine Resistant in Iran, Harboring Mutations in the Squalene Epoxidase () Gene.

Introduction: and are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance. We studied the antifungal susceptibility profiles in Iranian isolates of these two species.

Methods: A total of 96 and 45 isolates were subjected to molecular typing by ribosomal ITS region.