Publications by authors named "Ali Reza Salimi-Khorashad"
Article Synopsis
- Saprophytic fungi can lead to hospital-acquired infections, especially in patients who are already at high risk.
- These infections can significantly increase both mortality rates and healthcare costs.
- The study identified various fungi species in hospital environments, some of which were resistant to antifungal treatments, highlighting the need for further research on environmental fungi levels and their link to patient infections.
Erratum for Badiee et al., "Multicenter Study of Susceptibility of Aspergillus Species Isolated from Iranian University Hospitals to Seven Antifungal Agents".
Microbiol Spectr
August 2023
Article Synopsis
- The study evaluated the antifungal activities of 8 agents against Candida species isolated from immunocompromised patients in Iran, collected from 10 university hospitals between December 2019 and December 2021.
- It identified 598 strains, with C. albicans being the most common, followed by C. glabrata and others, using PCR methods for identification and standard microdilution techniques for testing antifungal susceptibility.
- Results showed that caspofungin and voriconazole had the lowest minimum inhibitory concentration (MIC) values, indicating they are the most effective treatments compared to other antifungal agents in this region, while some isolates exhibited multiazole resistance but not pan-azole resistance.
Background: It is known that severe acute respiratory coronavirus 2 (SARS-CoV-2) is the viral strain responsible for the recent coronavirus disease 2019 (COVID-19) pandemic. Current documents have demonstrated that the virus causes a PGE2 storm in a substantial proportion of patients via upregulating cyclooxygenase-2 (COX-2) and downregulating prostaglandin E2 (PGE2)-degrading enzymes within the host cell.
Aim: Herein, we aimed to study how short-term treatment with celecoxib (Celebrex), a selective COX-2 inhibitor, affects demographic features, early symptoms, O saturation, and hematological indices of cases with COVID-19.
Aspergillus species are a major cause of life-threatening invasive infections and noninvasive diseases. This study seeks to investigate the frequency of Aspergillus species among Iranian patients and their susceptibility to seven antifungals. In a cross-sectional study, 233 Aspergillus isolates were collected from 11 university hospitals in Iran between 2018 and 2021.
View Article and Find Full Text PDFBackground: Iran was one of the first countries to be affected by COVID-19. Identifying factors associated with the severity of COVID-19 is effective in disease management. This study investigated the epidemiological and clinical features and factors related to the severity of COVID-19 in one of the less privileged areas in Iran.
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