Diabetes up-regulated collagen IV and laminin α5 genes in mRNA and protein levels in seminiferous tubules of C57BL/6 adult mice.

Diabetes is a disease associated with impairment of the male reproductive system that causes complications such as decreased testosterone, the diameter of the seminiferous tubule, libido, and fertility. Extracellular matrix (ECM) molecules are involved in testicular development and spermatogenesis. Laminin and collagen are key proteins in seminiferous tubule basement membrane and play an important role in spermatogenesis.

Evaluation of oxidative stress indices after exposure to malathion and protective effects of ascorbic acid in ovarian tissue of adult female rats.

Background: Malathion is one of organophosphate pesticides that is extensively used in farming and crops to control pests. Malathion induces oxidative stress in the various tissues such as the reproductive system.

Objective: To determine the effects of malathion on malondialdehyde (MDA) level and glutathione (GSH) content in female rat ovary tissue as well as to assess the protective role of Ascorbic Acid.

Protective effects of ascorbic acid and garlic extract against lead-induced apoptosis in developing rat hippocampus.

Lead exposure has negative effects on developing nervous system and induces apoptosis in newly generated neurons. Natural antioxidants (i.e.

Analysis of Amygdala Nucleus in the Rat Brain: A review study.

Amygdale is one of the limbic related sub-cortical nuclei lying in the depth of temporal lobe and rostral of the inferior horn of lateral ventricle. In fact, amygdale is a nucleus complex that plays an important role in the emotional response, anger, fear, regulation of cardiovascular system, memory processes and learning and in pathophysiology of many diseases such as epilepsy, schizophrenia, Alzheimer, anxiety and depression. With regard to important of the amygdala in many critical functions, the cerebral disease and because of ethical problems most studies were done on animal models especially rats.

Morphometrical study of polysialylated neural cell adhesion molecule positive cells in rat pups hippocampus following induction of seizure during pregnancy.

Background: The polysialylated neural cell adhesion molecule (PSA-NCAM) is expressed in developing brain. Fetal brain damage is caused by different conditions such as seizure and hypoxia. The present study was designed to investigate the effect of maternal seizures on the number of PSA-NCAM positive cells in pup's hippocampus.