Publications by authors named "Ali R Effendi"
Article Synopsis
- The study investigates how clinically relevant levels of bupivacaine and levobupivacaine affect norepinephrine release from cardiac nerves, which is crucial for heart function.
- Results showed that both anesthetics significantly reduced norepinephrine release and heart contractions, with their effects being comparable to tetrodotoxin, a known nerve blocker.
- The findings suggest that these local anesthetics can impair cardiac sympathetic transmission, which may contribute to their cardiotoxic effects in clinical settings.
