Publications by authors named "Ali Rıza Odabas"

Introduction: More frequent and/or longer hemodialysis (HD) has been associated with improvements in numerous clinical outcomes in patients on dialysis. Home HD (HHD), which allows more frequent and/or longer dialysis with lower cost and flexibility in treatment planning, is not widely used worldwide. Although, retrospective studies have indicated better survival with HHD, this issue remains controversial.

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Background: Training is essential for the safe and uncomplicated placement of hemodialysis catheters. This study explores the learning curve of this procedure.

Methods: In this prospective study, 60 patients who needed emergency hemodialysis without vascular access were included.

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Article Synopsis
  • The study aimed to compare clinical outcomes between peritoneal dialysis (PD) patients who had COVID-19 and a control group of PD patients without COVID-19, as there was limited data on this topic.
  • The research involved 223 patients (113 with COVID-19 and 110 controls) and found that while general characteristics were similar, the COVID-19 group had lower serum albumin and hemoglobin levels and more complications like respiratory symptoms and rehospitalization on day 28.
  • Over a 90-day period, mortality rates were low (1 death in the COVID-19 group), and although some health issues persisted for patients who had COVID-19, overall mortality did not significantly differ from the control group.
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Introduction: We aimed to study the characteristics of peritoneal dialysis (PD) patients with coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.

Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded.

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Purpose: Coronavirus disease 2019 (COVID-19) has a higher mortality in the presence of chronic kidney disease (CKD). However, there has not been much research in the literature concerning the outcomes of CKD patients in the post-COVID-19 period. We aimed to investigate the outcomes of CKD patients not receiving renal replacement therapy.

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Objectives: This study aims to determine whether COVID-19 patients with different initial reverse transcriptase-polymerase chain reaction (RT-PCR), computed tomography (CT) and laboratory findings have different clinical outcomes.

Materials And Methods: In this multi-center retrospective cohort study, 895 hospitalized patients with the diagnosis of COVID-19 were included. According to the RT-PCR positivity and presence of CT findings, the patients were divided into four groups.

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Background: In this study, we evaluated 3-month clinical outcomes of kidney transplant recipients (KTR) recovering from COVID-19 and compared them with a control group.

Method: The primary endpoint was death in the third month. Secondary endpoints were ongoing respiratory symptoms, need for home oxygen therapy, rehospitalization for any reason, lower respiratory tract infection, urinary tract infection, biopsy-proven acute rejection, venous/arterial thromboembolic event, cytomegalovirus (CMV) infection/disease and BK viruria/viremia at 3 months.

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Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.

Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19.

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Article Synopsis
  • Older adults with chronic kidney disease (CKD) and those on maintenance haemodialysis (HD) show a higher likelihood of severe COVID-19 outcomes compared to non-uraemic patients.
  • The study analyzed data from 879 hospitalized COVID-19 patients, revealing that older individuals in the CKD and HD groups experienced significantly greater rates of severe illness and ICU admissions than the control group.
  • In-hospital mortality rates were also notably elevated in older patients with CKD and HD, indicating a critical need for targeted healthcare strategies for these vulnerable populations.
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Background: We aimed to present the demographic characteristics, clinical presentation, and outcomes of our multicenter cohort of adult KTx recipients with COVID-19.

Methods: We conducted a multicenter, retrospective study using data of patients hospitalized for COVID-19 collected from 34 centers in Turkey. Demographic characteristics, clinical findings, laboratory parameters (hemogram, CRP, AST, ALT, LDH, and ferritin) at admission and follow-up, and treatment strategies were reviewed.

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Article Synopsis
  • Hospital-acquired acute kidney injury (HA-AKI) is common in Covid-19 patients, with significantly higher mortality rates observed among chronic kidney disease (CKD) patients compared to those without CKD.
  • In a study of 621 hospitalized Covid-19 patients, 32.5% developed HA-AKI, with rates being 48.0% in CKD patients versus 17.6% in non-CKD patients.
  • The highest mortality rate (41.1%) was found in CKD patients with HA-AKI, indicating that both HA-AKI and CKD worsen outcomes for patients hospitalized due to Covid-19.
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Background: Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics and determinants of mortality in a large group of MHD patients hospitalized for COVID-19.

Methods: This multicenter, retrospective, observational study collected data from 47 nephrology clinics in Turkey.

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Background: Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand as one of the established potential risk factors for severe coronavirus disease 2019 (COVID-19). Case morbidity and mortality rates for any type of infection have always been much higher in CKD, haemodialysis (HD) and RT patients than in the general population. A large study comparing COVID-19 outcome in moderate to advanced CKD (Stages 3-5), HD and RT patients with a control group of patients is still lacking.

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Background: The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from the databases of countries or centers. Here, we present the extended results of the Primary Glomerular Diseases Study of the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) Working Group.

Methods: Data of patients who underwent renal biopsy and received the diagnosis of PGD were recorded in the database prepared for the study.

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Donor and recipient artery problems are challenging complications in renal transplant patients. In this report, we present our treatment strategy in a 42-year-old renal transplant case with renal artery stenosis and a giant pseudoaneurysm at the anastomotic site. Open repair failed due to extreme adhesions.

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BACKGROUND Amyloidosis is a protein-misfolding disease characterized by the deposition of aggregated proteins in the form of abnormal fibrils that disrupt tissue structure, ultimately causing disease. Amyloidosis is very frequent in untreated familial Mediterranean fever (FMF) patients and it is the most important feature that determines the prognosis of FMF disease. The mean platelet volume (MPV) in FMF has been previously studied.

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Purpose: Hemodialysis (HD) patients are known to have high cardiovascular mortality rate. Sudden cardiac death (SCD) due to arrhythmias causes most of the cardiac deaths. HD per se may lead to ECG abnormalities and ventricular arrhythmias.

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Background: Hyperuricemia is an independent predictor of impaired fasting glucose and type 2 diabetes, but whether it has a causal role in insulin resistance remains controversial. Here we tested the hypothesis that lowering uric acid in hyperuricemic nondiabetic subjects might improve insulin resistance.

Methods: Subjects with asymptomatic hyperuricemia (n = 73) were prospectively placed on allopurinol (n = 40) or control (n = 33) for 3 months.

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Background: Erythropoiesis-stimulating agents (ESA) are commonly used for the treatment of anemia in hemodialysis (HD) patients, however, 5-10% of these patients have resistance to ESA treatment. Hepcidin and neutrophil-gelatinase associated lipocalin (NGAL) are induced by inflammation and these proteins may take role in ESA resistance. Herein, we aimed to investigate the effects of serum hepcidin, NGAL, transferrin and C-reactive protein (CRP) levels on ESA resistance in HD patients.

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Introduction: Glomerulonephritis is still the primary cause among the diseases causing end stage renal disease. Helicobacter pylori (HP), also having a local proinflammatory effect on gastric mucosa, can trigger a local and systemic inflammatory response, and consequently have a role in the development of extragastrointestinal defects.

Material And Methods: The study was composed of patients diagnosed with primary glomerulonephritis who had dyspeptic complaints throughout the diagnosis.

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Aim: To investigate the nature of dyslipidemia and its diversity in patients with systemic AA amyloidosis.

Methods: The reports of the kidney biopsies performed due to nephrotic proteinuria (>3.5 g/day/1.

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Objective: AA amyloidosis occurs in the setting of longstanding inflammation. An increased incidence of coronary artery disease (CAD) was noted in patients with chronic inflammatory disease (CID). Retrobulbar blood flow predicts future macrovascular events including CAD.

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