Objective: Topiramate (TPM) is a new antiepileptic drug, which has a wide spectrum of activities suggesting a potentially valuable therapeutic profile. Our objective is to report our experience in treating children with intractable epilepsy.
Methods: Prospective, open label, add on trial of TPM in treating consecutive children with intractable epilepsy (defined as recurrent seizures after at least 3 antiepileptic medication trials) seen between May 1, 1999 and April 28, 2002 at King Faisal Specialist Hospital and Research Centre and King Abdulaziz University Hospital in Jeddah, Kingdom of Saudi Arabia.
Objective: To identify high risk groups for the development of convulsive status epilepticus (CSE) in an attempt to decrease the incidence and to determine both the time to access to medical care and the use of prehospital treatment in an attempt to reduce the duration of seizing.
Methods: Retrospective study record analysis of all cases of CSE in children, at the King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia from June 1997 to June 2000.
Results: During the study period there were 24 cases of CSE.