IFN-γ enhances the anti-tumour immune response of dendritic cells against oral squamous cell carcinoma.

Objective: To investigate the expression of antigen processing-1 (Tap-1) and Tapasin in oral squamous cell carcinoma (OSCC), and observe the immune response against OSCC by use of IFN-γ-antigen induced dendritic cells (DCs) in vitro and in vivo.

Design: Expression of Tap-1 and Tapasin in different cell lines was analysed. CAL27 cells were treated with IFN-γ.