Publications by authors named "Ali Mokdad"

Importance: Homicide is one of the leading causes of death in the US, especially among adolescents and adults younger than 45 years. While geographic, racial and ethnic, and sex differences in homicide rates have been documented, a comprehensive assessment across all sociodemographics is needed.

Objective: To assess variation in US homicide rates from 2000 to 2019 across geographic location, race and ethnicity, sex, and age.

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Background: The COVID-19 pandemic induced an increase in telemedicine use in the American health care system. We assess disparities in telemedicine usage, the diseases and conditions it is used for, and the association of payment parity policies with telemedicine use for January 2019-March 2023.

Methods: We include health systems which reported electronic health record data to the Healthjump database.

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Background: Current evaluation tools are inadequate for assessing the impact of small-scale interventions, such as farmer's markets or community meal programs, on fruit and vegetable consumption. This study analyzes the pilot data of a novel tool designed to evaluate community-based programs' impact on fruit and vegetable consumption. Our research addresses the gap in effective evaluation methods for dietary behaviors within underserved populations.

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Importance: Understanding the drivers of health care spending across US counties is important for developing policies and assessing the allocation of health care services.

Objective: To estimate the amount of cross-county health care spending variation explained by (1) population age, (2) health condition prevalence, (3) service utilization, and (4) service price and intensity.

Design, Setting, And Participants: In this cross-sectional study, data for 4 key drivers of per capita spending were extracted for 3110 US counties, 148 health conditions, 38 age-sex groups, 4 payers, and 7 types of care for 2019.

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Importance: Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, highlighting inequalities, and developing strategies for lowering health spending.

Objective: To estimate US health care spending for each of 3110 US counties, across 4 payers (Medicare, Medicaid, private insurance, and out-of-pocket payments), and according to 148 health conditions, 38 age/sex groups, and 7 types of care from 2010 to 2019.

Design, Setting, And Participants: Observational analysis using more than 40 billion insurance claims and nearly 1 billion facility records.

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Objective: Diabetes is a leading cause of death in the U.S. Previous studies have found substantial racial, ethnic, and geographical disparities in diabetes mortality; however, research considering racial, ethnic, and geographical disparities simultaneously has been limited.

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Background And Objectives: The study aimed to identify key drivers of vaccine hesitancy among healthcare workers (HCWs) employed at long-term care facilities (LTCFs) within selected states. It also sought to determine which interventions, policies, and programs effectively reduced HCW vaccine hesitancy for coronavirus 2019 disease (COVID-19) and influenza.

Research Design And Methods: The study employed a mixed methods approach, combining secondary analysis of the Behavioral Risk Factor Surveillance System (BRFSS) data, survey research, and focus groups.

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Objectives: This study analyzes survey data across 21 countries to explore correlations between delays in blood testing and the prevalence of seven health conditions: thalassaemias, sickle cell disorders, malaria, HIV, high fasting plasma glucose, impaired kidney function, and high LDL cholesterol.

Methods: We analyzed Pandemic Recovery Survey data via multivariable logistic regression to compare blood test delays between individuals with and without medical conditions, while adjusting for sociodemographic factors. We also examined the disease burden using disability-adjusted life years (DALYs) and summary exposure values (SEV) rates.

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Background: Nearly two decades ago, the Eight Americas study offered a novel lens for examining health inequities in the USA by partitioning the US population into eight groups based on geography, race, urbanicity, income per capita, and homicide rate. That study found gaps of 12·8 years for females and 15·4 years for males in life expectancy in 2001 across these eight groups. In this study, we aimed to update and expand the original Eight Americas study, examining trends in life expectancy from 2000 to 2021 for ten Americas (analogues to the original eight, plus two additional groups comprising the US Latino population), by year, sex, and age group.

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Objectives: During the COVID-19 pandemic, essential health services experienced significant disruptions, impacting preventive and chronic care across the world.

Methods: Utilizing the Pandemic Recovery Survey (PRS), conducted online with Facebook's Active User Base across 21 countries between March and May 2023, this cross-sectional study identifies the magnitude of and key factors associated with unmet preventive and chronic care needs during the late stage of the COVID-19 pandemic.

Results: Approximately 28.

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Background: The Human Development Index (HDI)-a composite metric encompassing a population's life expectancy, education, and income-is used widely for assessing and comparing human development and wellbeing at the country level, but does not account for within-country inequality. In this study of the USA, we aimed to adapt the HDI framework to measure the HDI at an individual level to examine disparities in the distribution of wellbeing by race and ethnicity, sex, age, and geographical location.

Methods: We used individual-level data on adults aged 25 years and older from the 2008-21 American Community Survey (ACS) Public Use Microdata Sample.

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Background: While TB-related mortality in the US declined four-fold from 1990 to 2019, country-level estimates of TB burden obscure within-state racial heterogeneity and changes in TB burden over time. In sixteen US Southern States and Washington DC, the effects of health inequities engendered by Jim-Crow laws enacted from the late 1800s to the 1960s have not been evaluated for TB-related mortality. We, therefore, sought to compare TB mortality rates and annualized rate of change (AROC) between 1990 and 2019 in former Jim-Crow vs.

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Article Synopsis
  • Liver cancer is a major health crisis in Mongolia, with the country reporting the highest age-standardized disability-adjusted life-years (DALYs) for liver cancer globally in 2019, reflecting a severe public health burden.* -
  • Analysis revealed that alcohol consumption, as well as viral hepatitis B and C, significantly contribute to liver cancer cases in Mongolia, with alcohol-related DALYs being 29 times higher than the global average, and hepatitis-related cases also vastly increased compared to global statistics.* -
  • The study indicated a continuous rise in liver cancer incidence and deaths over the past 30 years, with specific trends showing higher rates in males for alcohol and hepatitis B, while females had higher incidences of hepatitis C and non
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Background: Numerous social and behavioral factors have been implicated in vaccination coverage. There is no single measure that describes a country's ability to improve or maintain its immunization coverage.

Methods: We estimated the "Vaccination Improvement Potential" (VIP) by taking the geometric mean of 13 different indicators on health financing, vaccine confidence, and socio-demographics for more than 200 countries across 30 years.

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Background: The economic crisis that began in 2008 has severely affected Southern (Greece, Italy, Portugal, Spain) Western European (SWE) countries of Western Europe (WE) and may have affected ongoing efforts to eliminate viral hepatitis. This study was conducted to investigate the impact of the economic crisis on the burden of HBV and HCV disease.

Methods: Global Burden of Diseases 2019 data were used to analyse the rates of epidemiological metrics of HBV and HCV acute and chronic infections in SWE and WE.

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Introduction: Intracranial hemorrhage (ICH), a serious complication in persons with hemophilia A (PWHA), causes high rates of mortality and morbidity. Identified ICH risk factors from patient data spanning 1998-2008 require reassessment in light of changes in the current treatment landscape.

Aim And Methods: PWHA identified in the ATHNdataset were evaluated retrospectively to assess incidence of ICH and determine the association between ICH risk and key characteristics using time-to-event analyses (Cox proportional-hazards models, survival curves, and sensitivity analyses).

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Importance: Stroke is a leading cause of death and disability in the US. Accurate and updated measures of stroke burden are needed to guide public health policies.

Objective: To present burden estimates of ischemic and hemorrhagic stroke in the US in 2019 and describe trends from 1990 to 2019 by age, sex, and geographic location.

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Objective: Monitoring trends in key population health indicators is important for informing health policies. The aim of this study was to examine population health trends in Canada over the past 30 years in relation to other countries.

Methods: We used data on disability-adjusted life years (DALYs), years of life lost (YLL), years lived with disability, life expectancy (LE), and child mortality for Canada and other countries between 1990 and 2019 provided by the Global Burden of Disease Study.

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Article Synopsis
  • The study assessed the health impact of kidney dysfunction as a metabolic risk factor in 21 countries of the North Africa and Middle East region between 1990 and 2019, utilizing data from the Global Burden of Disease 2019 study.
  • In 2019, kidney dysfunction led to approximately 296,632 deaths in the region, reflecting a significant increase since 1990, with countries like Afghanistan and Egypt showing the highest death rates associated with this condition.
  • The findings highlighted the role of kidney dysfunction in contributing to various cardiovascular diseases, urging policymakers to enhance prevention and management strategies to mitigate its broader health implications.
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Background: Obesity-related cancers in the 16 Southern African Development Community (SADC) countries is quite prominent. The changes and time trends of the burden of obesity-related cancers in developing countries like SADC remain largely unknown. A descriptive epidemiological analysis was conducted to assess the burden of obesity-related cancers, (liver, esophageal, breast, prostate, colon/rectal, leukemia, ovarian, uterine, pancreatic, kidney, gallbladder/biliary tract, and thyroid cancers) in SADC countries.

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Purpose: The aim of this study is to investigate drug use disorders which are a major cause of Disability Adjusted Life Years (DALYs) in the Eastern Mediterranean Region (EMR).

Methods: This article is a part of the global burden of diseases (GBD), injuries, and risk factors 2019 study. The GBD modeling approach was used to estimate population-level prevalence of drug use disorders.

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Objective: In this study, we sought to understand patterns of childhood vaccinations in the United States across socioeconomic and racial/ethnic groups over a 12-year period to identify interventions that improve immunization equity and inform public health practice.

Design: We conducted an explanatory, sequential, mixed-methods study. US state- and county-level immunization data were analyzed to understand trends in immunization coverage among racial/ethnic groups.

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Background: Road traffic accidents are a major public health problem globally, causing millions of injuries, deaths and disabilities, and a huge loss of financial resources, especially in low- and middle-income countries.

Aim: To determine the incidence of road traffic injuries and associated mortality from 1997 to 2020 in the Islamic Republic of Iran.

Methods: This retrospective study used data from the Legal Medicine Organization of the Islamic Republic of Iran to estimate the annual rates of road traffic injuries and associated mortality from 21 March 1997 to 20 March 2020.

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Objectives: This article describes key data sources and methods used to estimate hearing loss in the United States, in the Global Burden of Disease study. Then, trends in hearing loss are described for 2019, including temporal trends from 1990 to 2019, changing prevalence over age, severity patterns, and utilization of hearing aids.

Design: We utilized population-representative surveys from the United States to estimate hearing loss prevalence for the Global Burden of Disease study.

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